CASTRAÇÃO QUÍMICA, BIÓPSIA SEM DOR E TUMOR QUE NÃO PRECISA SER OPERADO: A VERDADE QUE NINGUÉM CONTA

What you will learn in this video: 00:00 — Introduction: continuation of the series on advances in prostate cancer treatment 01:10 — What is hormone blockade (hormone therapy) and why the term "chemical castration" is scary — and what it really means 03:45 — How central testosterone blockade works and its side effects (hot flashes, depression, loss of muscle and bone mass) 06:20 — Why testosterone is the "fuel" of prostate cancer — and how to block it since 1941 08:00 — Prostate biopsy: does it hurt? How is it done? Sedation, anesthesia, and the number of fragments removed 10:30 — Transrectal biopsy vs. transperineal biopsy: which is safer and why has transperineal biopsy practically eliminated infections? 13:15 — Access to and health plan coverage for transperineal biopsy in Brazil 15:00 — Darolutamide, enzalutamide, apalutamide, and abiraterone: what are the practical differences between the new oral drugs for hormone blockade? 19:30 — How does the oncologist choose the right drug for each patient (comorbidities, drug interactions, access, and generics)? 22:00 — Active surveillance: is it safe to leave the tumor unoperated? Criteria from the Canadian study with 20 years of follow-up 26:15 — When active surveillance is NOT indicated: High PSA, aggressiveness variants, intraductal carcinoma, cribriform carcinoma, and BRCA2 mutation 29:40 — PSMA-PET and magnetic resonance imaging as tools for decision-making before entering active surveillance 32:00 — Is metastatic prostate cancer curable? What has changed in the last decade with radioisotopes, Radium-223 and Lutetium-PSMA 35:10 — From 2 lines of treatment to up to 5: how drug sequencing prolongs survival 37:30 — Precision medicine and genetic analysis: an optimistic look at the future of oncology ⚠️ This content is for educational purposes only and does not replace medical consultation. Each case is unique and should be evaluated by a specialist. 🔸 Institutional Footer ☎ (11) 2769-3929 | 📱 (11) 99590-1506 | 📲 WhatsApp: https://bit.ly/2OIObBx 💻 www.clinicauroonco.com.br | 📅 Schedule your appointment 📍 R. Borges Lagoa 1070, Cj. Cobertura, Vila Mariana — São Paulo — SP We are specialists in uro-oncology and robotic surgery, serving patients from all over Brazil. Contact our team through the website, phone or WhatsApp to schedule an in-person or telehealth appointment. Consider becoming a member of our YouTube channel. We have a weekly live stream to answer questions about prostate cancer, in addition to exclusive content for subscribers. 👉 Click here to become a member Dr. Bruno Benigno | Urologist | CRM SP 126265 | RQE 60022 Dr. Lígia Toledo | Clinical Oncologist Uro Onco Clinic Team — São Paulo — SP