8 Drugs Which Worsen Multiple Sclerosis

TNF alpha inhibitors 0:29 Gamma interferons 1:57 GM-CSF (filgastrim or neupogen) 2:51 PKM2 activators (TEPP-46 and DASA-58) 4:14 Yellow fever vaccine 5:16 Immune Checkpoint Inhibitors 6:09 Gilenya, Mayzent, Zeposia 7:49 Tysabri 9:11 Sources: Modulation of PKM activity affects the differentiation of TH17 cells: https://www.science.org/doi/10.1126/s... Promising MS Drug Could Worsen Disease, Research Suggests: https://newsroom.uvahealth.com/2020/1... The Role of Granulocyte-Macrophage Colony-Stimulating Factor in Murine Models of Multiple Sclerosis: https://www.ncbi.nlm.nih.gov/pmc/arti... Severe exacerbation of relapsing-remitting multiple sclerosis after G-CSF therapy: https://www.ncbi.nlm.nih.gov/pmc/arti... Multiple sclerosis flares associated with recombinant granulocyte colony-stimulating factor: https://www.researchgate.net/publicat... Tumor Necrosis Factor Alpha Blockade and Multiple Sclerosis: Exploring New Avenues: https://www.cureus.com/articles/69439... Anti-Tumor Necrosis Factor Alpha-Associated Multiple Sclerosis: http://www.ajnr.org/content/26/6/1548 Treatment of multiple sclerosis with gamma interferon: exacerbations associated with activation of the immune system: https://pubmed.ncbi.nlm.nih.gov/3110648/ Yellow fever vaccination and increased relapse rate in travelers with multiple sclerosis: https://pubmed.ncbi.nlm.nih.gov/21670... Risk of MS relapse after yellow fever vaccination A self-controlled case series: https://nn.neurology.org/content/7/4/... Comment or ask questions below! I would be happy to answer! Subscribe on YouTube for more videos every Wednesday! Make video requests in the comments section! My book "Resilience in the Face of Multiple Sclerosis" on Amazon: https://www.amazon.com/dp/B07WP7H5LK Dr. Brandon Beaber is a board-certified neurologist with subspecialty training in multiple sclerosis and other immunological diseases of the nervous system. He is a partner in the Southern California Permanente Medical Group and practices in Downey, California (South Los Angeles). He has several publications on MS epidemiology and has participated in clinical trials for MS therapeutics. You can follow him on twitter @Brandon_Beaber where he regularly posts about MS news and research. Follow me on twitter:   / brandon_beaber   Music: INNER GRACE - Copyright 2018 Wilton Vought Source: Really Really Free Music Link:    • Video   T he video material by Dr. Brandon Beaber is general educational material on health conditions and is not intended to be used by viewers to diagnose or treat any individual's medical condition. Specifically, this material is not a substitute for individualized diagnostic and treatment advice by a qualified medical/health practitioner, licensed in your jurisdiction, who has access to the relevant information available from diagnostic testing, medical interviews, and a physical examination. To the extent that Dr. Beaber endorses any lifestyle change, behavioral intervention, or supplements, the viewer should consult with a qualified healthcare professional to determine the safety and efficacy of the intervention in light of their individualized information.