Physiology of Skull Base Leaks vs Spinal CSF Leaks — Dr. Peter Kranz

Dr. Peter Kranz presented this talk on the “Physiology of Skull Base Leaks vs Spinal CSF Leaks” at the 2025 Intracranial Hypotension Conference on June 28, 2025 in Amsterdam, The Netherlands. The 2025 Intracranial Hypotension conference was put on by Cedars-Sinai, Duke University, University of Freiburg, and University of Amsterdam. The Spinal CSF Leak Foundation supported this conference with an educational grant. 0:00 Introduction 1:05 Factors Controlling CSF Physiology 4:12 CT Evidence in Humans 6:27 Effect on Thecal Sac 8:08 Summary of Venous Outflow 8:38 Queckenstedt's Test 10:21 CSF Hydrodynamics and Pressure Points 13:34 Implications for Skull Base Leaks 16:05 Types of Skull Base Leaks 17:36 Case Study: Child with Meningocele 20:23 Dural Enhancement in Skull Base Leaks 20:51 Conclusion