FÍGADO - EXAME BARATO pode revelar seu FÍGADO antes dos sintomas aparecerem (médico mostra como ler)

✅Become a member of this channel and get benefits, exclusive content, access to the Whatsapp group and 2 exclusive monthly live streams:    / @dralaindutra   WHAT TO INVESTIGATE IN THE LIVER IN 4 LAYERS Layer 1 — Direct Liver AST, ALT and GGT Layer 2 — Fibrosis Risk FIB-4 CALCULUS Age, AST, ALT and Platelets Layer 3 — Metabolic Terrain Fasting Insulin, Triglycerides, HDL, Ferritin and Uric Acid Layer 4 — Causes that often go unnoticed Alcohol, Medications in use, Supplements in use, Hepatitis B and Hepatitis C. In this video, I show how to investigate fatty liver, hepatic fibrosis and metabolic risk. with inexpensive tests that are often already part of your check-up, but that almost no one interprets together. I also explain why the liver is a silent organ, why so many people have fatty liver disease without symptoms, and how insulin resistance connects with fatty liver, diabetes, metabolic syndrome, and inflammation. SCIENTIFIC REFERENCES Gawrieh S, Wilson LA, Cummings OW, Clark JM, Loomba R, et al. (NASH CRN) (2019). Histologic Findings of Advanced Fibrosis and Cirrhosis in Patients With NAFLD Who Have Normal Aminotransferase Levels. Am J Gastroenterol. PMID: 31517638. DOI: 10.14309/ajg.0000000000000388 Lonardo A. (2024). Alanine aminotransferase predicts incident steatotic liver disease of metabolic etiology. World J Gastroenterol. PMID: 38983954. DOI: 10.3748/wjg.v30.i24.3016 Kunutsor SK, Abbasi A, Adler AI. (2014). Gamma-glutamyl transferase and risk of type II diabetes: updated systematic review and dose-response meta-analysis. Ann Epidemiol. PMID: 25263236. DOI: 10.1016/j.annepidem.2014.09.001 Kwak J, Seo IH, Lee YJ. (2023). Serum GGT and incidence of metabolic syndrome over 12 years. Diabetol Metab Syndr. PMID: 36823659. DOI: 10.1186/s13098-023-01000-5 Long Y, Zeng F, Shi J, Tian H, Chen T. (2014). Gamma-glutamyltransferase predicts increased risk of mortality: systematic review and meta-analysis. Free Radic Res. PMID: 24684379. DOI: 10.3109/10715762.2014.902055 Ballestri S, Targher G, Lonardo A, et al. (2016). NAFLD is associated with an almost twofold increased risk of incident type 2 diabetes and metabolic syndrome. J Gastroenterol Hepatol. PMID: 26667191. DOI: 10.1111/jgh.13264 Sterling RK, et al. (2006). Development of a simple noninvasive index to predict significant fibrosis. Hepatology. PMID: 16729309 Shah AG, et al. (2009). Comparison of noninvasive markers of fibrosis in NAFLD. Clin Gastroenterol Hepatol. PMID: 19523535 McPherson S, et al. (2017). Age as a confounding factor for the accurate noninvasive diagnosis of advanced NAFLD fibrosis. Am J Gastroenterol. PMID: 27725647 Kanwal F, et al. (2021). Clinical Care Pathway for the Risk Stratification and Management of Patients With NAFLD. Gastroenterology. PMID: 34602251 Peck-Radosavljevic M. (2016). Thrombocytopenia in chronic liver disease. Liver Int. PMID: 27860293 Mitchell O, Feldman DM, Diakow M, Sigal SH. (2016). The pathophysiology of thrombocytopenia in chronic liver disease. Hepat Med PMID: 27186144 Stefan N, Cusi K. (2022). A global view of the interplay between NAFLD and type 2 diabetes. Lancet Diabetes Endocrinol. PMID: 35183303 Song Z, et al. (2025). TyG index and incident MASLD. Cardiovasc Diabetol. PMID: 40181314 Ma X, et al. (2024). TG/HDL ratio and incident MAFLD. BMC Gastroenterol. DOI: 10.1186/s12876-024-03471-w Darmawan G, Hamijoyo L, Hasan I. (2017). Association between serum uric acid and NAFLD. Acta Med Indonesia. PMID: 28790228 Kowdley KV, et al. (2012). Serum ferritin is an independent predictor of histologic severity and advanced fibrosis in NAFLD. Hepatology. PMID: 21953442. DOI: 10.1002/hep.24706 Moirand R, et al. (1997). A new syndrome of liver iron overload with normal transferrin saturation. Lancet. PMID: 8996422 Zimmerman HJ, Maddrey WC. (1995). Acetaminophen hepatotoxicity with regular alcohol use. Hepatology. PMID: 7657281 Chon YE, et al. (2024). Diagnostic accuracy of VCTE (FibroScan) for fibrosis in NAFLD. Clin Mol Hepatol. PMID: 39165159. DOI: 10.3350/cmh.2024.0392 Hernaez R, et al. (2011). Diagnostic accuracy and reliability of ultrasonography for fatty liver. Hepatology. DOI: 10.1002/hep.24452 ⚠️LEGAL DISCLAIMER⚠️ The medical information contained in this video is for general informational purposes only and should not be used for any diagnostic or treatment purpose. This information does NOT create any doctor-patient relationship and should not be used as a substitute for professional diagnosis or treatment. Please consult your doctor before making any healthcare decisions and do NOT stop any medication without your doctor's consent. Medicine is a constantly evolving science; the videos are produced based on the most recent scientific articles to date. Dr. Alain Dutra - CREMESP 102211. RQE 27294