NIBRT | Use of ZipChip CE/ESI-MS as a Flexible Tool for Therapeutic Protein Characterization

Learn more at https://www.repligen.com/zipchip Hear from Sara Carillo, PhD, Applications Development Team Leader, how ZipChip capillary electrophoresis can be used as a powerful tool for therapeutic protein characterization, paired with Thermo Fisher Scientific Q Exactive Plus mass spectrometer. Process Analytical Technology (PAT) for At-line Bioprocess Analysis PATsmart ZipChip efficiently separates and seamlessly introduces samples into your mass spectrometer with electrospray ionization (ESI). Common challenging analyses are made easy, including protein separation for biopharmaceutical critical quality attributes (CQA), Charge Variant Analysis, and metabolite quantification from biological matrices. Experience a powerful alternative to liquid chromatography mass spectrometry (LC MS). What is PAT? Process Analytical Technology, or PAT, are systems or technologies that you can integrate into your bioprocess in order to monitor, manage, and potentially automate and better understand your process and its behaviors. Having PAT in place allows you to measure multiple critical parameters, optimize feed strategies, reduce costly off-line testing delays, and more! Learn more about ZipChip and PATsmart Analytical Solutions at https://www.repligen.com/solutions/pr... VD0164 eRev. 1.0