2026 ASCO Prostate Cancer Highlights

The Lank Center for Genitourinary Oncology at Dana-Farber Cancer Institute presents a succinct summary of all the prostate cancer clinical updates you need to know from ASCO 2026. Highlights in this video include: PROTEUS: Perioperative Apalutamide + ADT improves pathologic CR and metastasis free survival compared to ADT + placebo in high risk localized prostate cancer TALAPRO-3: Talazoparib + Enzalutamide improves rPFS compared to Enzalutamide in HRR deficient mCSPC A-DREAM: ADT + ARPI Interruption in pts with mCSPC PSA less than 0.2 leads to Treatment Free with Eugonadal Test in 41% ARACOG: ADT + Darolutamide associated with less cognitive decline that ADT + Enzalutamide REDUSE: Denosumab q12weeks was non inferior to denosumab q4 weeks in metastatic breast and prostate cancer

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