Derek Dicker & Vik Malyala | Beyond the GPU

In this interview from Beyond the GPU: The Full-Stack Fight for Enterprise AI 2026, Derek Dicker, corporate vice president of the Enterprise Business Group at Advanced Micro Devices Inc., joins Vik Malyala, chief business officer at Super Micro Computer Inc., to talk with theCUBE's Dave about how AMD and Supermicro are uniting CPU and GPU architectures for enterprise AI. Dicker explains why data center modernization has become a prerequisite for AI deployment, citing consolidation results where a single fifth-generation EPYC server replaces eight legacy servers while cutting power by 70%. Malyala details how demand has shifted from training clusters toward agentic inferencing, pushing customers to optimize cost per token and total cost of ownership. The conversation explores how CPUs are becoming essential to agentic AI, handling orchestration, tool calls and data movement so GPUs stay fed with work rather than idle. Dicker and Malyala break down Venice, AMD's sixth-generation EPYC processor, and how it translates into Supermicro's H15 server family and the Helios rack-scale architecture pairing 72 GPUs with 18 Venice CPUs. They also touch on the deep co-engineering process spanning silicon design, validation and BIOS optimization, along with the growing need for liquid cooling and retrofitted data centers as rack density climbs past 40,000 cores. From consolidation playbooks to rack-scale deployability, Dicker and Malyala make the case that enterprises can't afford to wait to modernize their infrastructure for the agentic AI era. Find more SiliconANGLE news and analysis https://siliconangle.com/ Follow theCUBE's wall-to-wall event coverage https://siliconangle.com/events/ Learn about the latest theCUBE events https://www.thecube.net/ 00:00 - Title: "Advancing AI: Infrastructure, Innovation, and Partnerships 02:33 - Navigating the Surge: Scaling AI Infrastructure Amid Rising Demand 06:20 - Harmonizing CPU and GPU in AI Workloads 10:33 - Title: "In-Depth Exploration of AMD and Supermicro's Engineering Collaboration 17:23 - Venice and H15: Advancements in Deployability 26:45 - Rack Scale Transformation: Embracing Helios for Enhanced Computing 34:59 - Harmonizing Tradition and Innovation: Evolving Workloads with AI 43:52 - Liquid Cooling Innovations: Shaping Future Data Center Strategies #theCUBE #SupermicroAMD #theCUBEresearch #AMD #Supermicro #AIInfrastructure #EnterpriseAI