Can We 3D Print Human Organs? Dr. Stephanie Willerth on Bioprinting & Tissue Engineering | Ep. 11
Imagine a future where we can 3D print organs, heal spinal cord injuries, and test new drugs without animal models. That future is closer than you think. In this episode of In Vivo, Dr. Stephanie Willerth explains how bioprinting is transforming regenerative medicine, tissue engineering, and personalized healthcare. Topics Covered: How bioprinting works & how it differs from traditional 3D printing The role of stem cells in regenerative medicine & personalized implants How scientists are printing functional tissues & even organs Why bioprinting could replace animal testing in drug discovery The biggest challenges in scaling up bioprinted organs for transplantation How bioprinted tissues could be used for disease modeling & personalized medicine The future of biofabrication & clinical applications of 3D-printed tissues About Dr. Stephanie Willerth: Dr. Stephanie Willerth is a professor at the University of Victoria and the CEO of Axolotl Biosciences, a leader in bioprinting innovation. Her work in tissue engineering, stem cells, and biomaterials is pushing the boundaries of modern medicine. Listen in to explore how 3D printing is reshaping medicine, from organ regeneration to personalized drug testing. Introduction to Bioprinting and Tissue Engineering - 00:00:00 Defining Regenerative Medicine, Tissue Engineering, and Bioprinting - 00:02:06 Differences Between Traditional 3D Printing and Bioprinting - 00:03:57 The Role of Bioprinting in Tissue Culture Evolution - 00:05:53 Potential Applications of Bioprinting in Healthcare - 00:06:14 Challenges of Bioprinting Complex Organs - 00:07:26 The Importance of Stem Cells in Bioprinting - 00:09:42 Engineering Stem Cells for Immune Compatibility - 01:10:40 Bio Ink Definition and Function - 01:13:13 Resolution in Tissue Printing - 01:13:53 Differentiation of Stem Cells in Bioprinting - 01:14:56 Current State and Future of Bioprinting - 01:17:24 Bioprinting for Drug Screening and Disease Modeling - 01:18:24 Predictive Health Applications with Bioprinted Tissues - 01:19:54 Integration of Multiple Cell Types in Large Structures - 01:22:13 Genetics vs. Scientist Intervention in Tissue Development - 01:24:23 Monitoring and Assessing Printed Tissues - 01:26:22 Easiest and Hardest Tissues to Print - 01:28:37 Therapeutic Applications of Bioprinting in Hospitals - 01:32:07 Synergy Between Bioprinting and Brain-Computer Interfaces - 01:37:40 Bioprinting as a Tool for Testing and Development - 01:40:58 The Viability of Bioprinted Food - 01:43:54 Personal Journey into Bioprinting and Entrepreneurship - 01:46:17 Transitioning from Academia to Industry - 01:49:19 Future Adoption of Bioprinting in Medical Facilities - 01:54:24 Advice for Students and Skills for Bioprinting - 01:57:49 Open Source in Bioprinting and Ethical Concerns - 01:00:00 Hopes for Bioprinting in the Next Decade - 01:03:02 Contact Information and Lab Tours - 01:06:41 Closing Remarks - 01:06:58 Dr. Willerth's Lab - https://www.engr.uvic.ca/~willerth/ Dr. Willerth on X - https://x.com/DrWillerth Handbook of Neural Engineering: A Modern Approac by Dr. Willerth - https://www.amazon.ca/Handbook-Neural... Axolotl Biosciences - https://www.axolotlbiosciences.com/home In Vivo on Spotify - https://open.spotify.com/show/5GBvPPv... Attributions: Cellink - • The home of 3D bioprinting Engineers and Geoscientists BS - • 2021 President's Awards | Teaching Award o...

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