T3 na Depressão: A Estratégia Mais Subestimada

📚Download your free Guide to Prescribing Psychotropic Drugs in the Real World here https://wa.me/553199727834?text=Ol%C3... In this video, I discuss the role of liothyronine (T3) as a potentiation strategy in treatment-resistant depression, bringing a practical, evidence-based perspective—which, in my view, is still underutilized in clinical psychiatry. Based on classic data such as STAR*D (step 3), it is clear that T3 presents a particularly interesting combination: efficacy comparable to other strategies and, most importantly, better tolerability. In practice, this translates into a lower dropout rate due to adverse effects when compared to lithium, something that directly impacts clinical outcomes. Furthermore, I discuss a point that often completely changes the patient's experience: the speed of response. T3 can produce initial improvement within a few days, making it especially useful in scenarios of refractoriness or significant functional impairment. Throughout the lesson, I organize the use of T3 in a practical way: when to prescribe it, how to start (including initial dose and titration), which tests to order, and how to monitor it safely. I also address patient selection criteria, cardiovascular risks, and absolute contraindications, which need to be considered before prescribing. More than reviewing the literature, the goal here is to structure clinical reasoning: when T3 should be included in the therapeutic algorithm and why, in many cases, it may be a more rational choice than more frequently used strategies. If you manage treatment-resistant depression in your practice, this video will help you incorporate an evidence-based tool that can improve both response and tolerability. 🔗 Instagram: @drrafaelgomespsiquiatra Dr. Rafael Q D Gomes Psychiatrist CRM/SP 169.787 – RQE 71.591 ⚠️ LEGAL NOTICE: The information contained in these videos is not intended to replace consultation with a medical professional or serve as a recommendation for any treatment plan. In accordance with the Medical Code of Ethics, the videos are for educational purposes only, and do not disclose addresses or telephone numbers of offices, clinics, or health services. The videos on this channel are produced based on Dr. Rafael Gomes' experience, practical observation of patients, and the most recent scientific research available at the time. If you have any questions, consult your doctor. ⚠️ Educational content aimed at healthcare professionals. Does not replace individualized ethical or legal evaluation.