Dystrophic Epidermolysis Bullosa: Disorder, Pathology, and Sub-types

#basementmembrane #skin #butterflyskin #epidermolysisbullosa #skinattachment #epidermolysis Introduction - 02:52 Pathogenesis - 06:03 Sub-types - 10:38 Intermediate Dystrophic EB - 11:23 Localised Dystrophic Junctional EB - 16:03 Recessive Dystrophic EB - 18:26 Severe Recessive Dystrophic EB - 19:40 Severe Recessive Dystrophic EB: SCC - 26:06 Inversa Recessive Dystrophic EB - 28:14 Combined Dominant and Recessive Dystrophic EB - 29:49 EB Pruriginosa - 32:01 Self-Improving Dystrophic EB - 33:48 Molecular Basis of Pathogenesis - 36:06 Mnemonic for Dystrophic EB sub-types - 37:18 Further Reading - 39:17 End - 40:20 Further Reading: 1. Chapter 69 – Genetic Blistering Disorders. In: Rooks Textbook of Dermatology, 10ed. Pg-69.1, Griffiths C et al. 2. Chapter 32 – Epidermolysis Bullosa. In: Bolognia’s Dermatology, 4ed. Pg-538, David Fine J et al. 3. Chapter 60 – Inherited Epidermolysis Bullosa. In: Fitzpatrick’s Dermatology, 9ed. Pg-1011, Marinkovish MP et al. 4. Shinkuma S. Dystrophic epidermolysis bullosa: a review. Clin Cosmet Investig Dermatol. 2015 May 26;8:275-84. doi: 10.2147/CCID.S54681. PMID: 26064063; PMCID: PMC4451851. 5. Yenamandra VK, Moss C, Sreenivas V, Khan M, Sivasubbu S, Sharma VK, Sethuraman G. Development of a clinical diagnostic matrix for characterizing inherited epidermolysis bullosa. Br J Dermatol. 2017 Jun;176(6):1624-1632. doi: 10.1111/bjd.15221. Epub 2017 May 5. PMID: 27925151. 6. EB Matrix: https://www.eb-clinet.org/resources/t...