Akiko Iwasaki: What Have We Learned About Long COVID?

Howie and Harlan are joined by Yale School of Medicine immunologist Akiko Iwasaki, a leading authority on vaccines and long COVID. Harlan reflects on America's crisis of trust in federal agencies; Howie provides some good news about bird flu. Links: Losing Trust Harlan Krumholz: "When Your Patient Dies" (https://www.jacc.org/doi/10.1016/j.ja...) "Federal Agents Stage Raid on Canal Street in New York City, Arresting 9" (https://www.nytimes.com/2025/10/21/ny...) "White House expands East Wing demolition as critics decry Trump overreach" (https://www.washingtonpost.com/politi...) "Americans' Job Ratings of Six Key U.S. Agencies Worsen" (https://news.gallup.com/poll/696059/a...) "NEJM and public health group are launching rival to CDC's MMWR publication" (https://www.statnews.com/2025/10/21/c...) "South Carolina measles outbreak rises as schools with low vaccination see new cases" (https://www.usatoday.com/story/news/n...) Akiko Iwasaki Health & Veritas Ep. 9: Dr. Akiko Iwasaki: Is Long COVID One Disease or Many? (https://insights.som.yale.edu/podcast...) "The Long COVID Puzzle: Autoimmunity, Inflammation, and Other Possible Causes" (https://www.yalemedicine.org/news/the...) "A New Kind of Clinical Trial: Bringing Long COVID Research Into Patients' Homes" (https://medicine.yale.edu/news-articl...) "New Evidence Supports Autoimmunity as One of Long COVID's Underlying Drivers" (https://medicine.yale.edu/news-articl...) "Scientist Dr. Akiko Iwasaki Joins SPEAR Study Group to Investigate Monoclonal Antibodies for Long COVID and COVID-19 Post-Vaccination Syndrome" (https://invivyd.gcs-web.com/news-rele...) "Long Covid: A parallel pandemic" (   • Long Covid: A parallel pandemic  ) "Effectiveness of Colchicine for the Treatment of Long COVID" (https://jamanetwork.com/journals/jama...) Akiko Iwasaki and Harlan Krumholz: "Nirmatrelvir–ritonavir versus placebo–ritonavir in individuals with long COVID in the USA (PAX LC): a double-blind, randomised, placebo-controlled, phase 2, decentralised trial" (https://www.thelancet.com/journals/la...) "Does Paxlovid Reduce Long COVID Symptoms? Yale-Led Trial Finds Out" (https://medicine.yale.edu/news-articl...) Akiko Iwasaki: "Unexplained post-acute infection syndromes" (https://pubmed.ncbi.nlm.nih.gov/35585...) "Post-Acute Infection Syndromes Will Be the Focus of New YSM Center" (https://medicine.yale.edu/news-articl...) CDC: ME/CFS Basics (https://www.cdc.gov/me-cfs/about/inde...) "Varicella-zoster virus reactivation and the risk of dementia" (https://www.nature.com/articles/s4159...) Akiko Iwasaki and Harlan Krumholz: "Immunological and Antigenic Signatures Associated with Chronic Illnesses after COVID-19 Vaccination" (https://www.medrxiv.org/content/10.11...) "A small study on Covid vaccine safety sparks an online tempest" (https://www.statnews.com/2025/02/24/p...) "We have 'post-vaccination syndrome.' We are tired of being used to score anti-vax points" (https://www.statnews.com/2025/06/10/y...) Health & Veritas Ep. 162: Paul Lombardo: Reckoning with the Dark History of Eugenics (https://insights.som.yale.edu/podcast...) Health & Veritas Ep. 163: Michael Dunne: Confronting the Antibiotic Resistance Crisis (https://insights.som.yale.edu/podcast...) Mayo Clinic: Alpha-gal syndrome (https://www.mayoclinic.org/diseases-c...) Akiko Iwasaki: Woman shares what it's like to live with alpha-gal meat allergy triggered by tick bite" (htt...