NIHR Oxford BRC Statistics Hub Seminar: Survival analysis techniques in clinical trials

This talk – Survival analysis techniques in clinical trials, from traditional methods to multi-state Markov modelling approaches - explored the evolution of survival analysis techniques in clinical trials, highlighting their crucial role in medical research. Dr Clement Twumasi, Medical Statistician in the Nuffield Department of Medicine, began with traditional methods like Kaplan-Meier estimates and Cox proportional hazards models, the foundational tools for analysing time-to-event data, before moving on to contemporary approaches, focusing on time-homogeneous and inhomogeneous multi-state Markov models. These models offer a nuanced view of patient trajectories through different health states, providing deeper insights into disease progression and treatment efficacy. This was part of a series of lunchtime seminars organised by the NIHR Oxford BRC Statistics Hub.