10.09 Stereochemistry of the Wittig Reaction

Simple Wittig reactions often favor the cis or (Z) alkene. This results from the avoidance of steric interactions in the transition state for nucleophilic addition of the ylide to the ketone or aldehyde. 00:00 Stereoselectivity in Wittig Olefination 01:04 Visualizing the Nucleophilic Addition Step