Alzheimer’s and Gum Disease: Exploring the Role of Oral Bacteria in Brain Health | Dr. Michael Detke

Could bacteria linked to gum disease play a role in Alzheimer’s disease? Emerging science suggests that P. gingivalis, a bacterium associated with gum disease, may contribute to inflammation and brain damage linked to Alzheimer’s disease. In this episode, Dr. Michael J. Detke of Lighthouse Pharma discusses the SPRING clinical trial and the investigational oral drug LHP588, which is being studied as a potential way to reduce bacteria-related brain damage. He also shares who may qualify for the study and what participation may involve for individuals with mild to moderate Alzheimer’s and their caregivers. To learn more, watch our full conversation with Dr. Detke, part of the Zoom In on Dementia and Alzheimer’s series: https://www.brightfocus.org/resource/... Support for Let’s Talk Alzheimer’s is provided by sponsors Lilly, Biogen, Eisai, and Genentech. Let’s Talk Alzheimer’s is presented by Alzheimer’s Disease Research, a BrightFocus Foundation program. We fund exceptional research across the globe to support the development of cutting-edge treatments, risk reduction strategies, and ultimately a cure for this mind-stealing disease. Visit brightfocus.org to learn more and get involved.

Medical breakthroughs and health stories | 60 Minutes Marathon
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Medical breakthroughs and health stories | 60 Minutes Marathon

Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard
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Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

Surgeon Reveals: Do THIS 1 Exercise for Poor Leg Circulation After 60
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Surgeon Reveals: Do THIS 1 Exercise for Poor Leg Circulation After 60

Watch his reaction when he’s told he’s a GOOD BOY for the first time 🥹
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Watch his reaction when he’s told he’s a GOOD BOY for the first time 🥹

Washington Week with The Atlantic full episode, July 10, 2026
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Washington Week with The Atlantic full episode, July 10, 2026

Medicine, Innovation & the Fight for Patient Care
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Medicine, Innovation & the Fight for Patient Care

Biomarkers, Imaging, and Early Treatment Decisions in Geographic Atrophy
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Biomarkers, Imaging, and Early Treatment Decisions in Geographic Atrophy

Yonatan Zeigen on Israel's new political party ("A Place For Us All") - Jung & Naiv: Episode 837
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Yonatan Zeigen on Israel's new political party ("A Place For Us All") - Jung & Naiv: Episode 837

Why Feedback Feels So Threatening in Vet Med (and What to Do About It) | Episode 95
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Why Feedback Feels So Threatening in Vet Med (and What to Do About It) | Episode 95

Understanding Macular Degeneration: A Listener Q&A Session
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Understanding Macular Degeneration: A Listener Q&A Session

The Burmese Python Is Disappearing in Florida at an Incredible Rate; the Real Culprit Surprises E...
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The Burmese Python Is Disappearing in Florida at an Incredible Rate; the Real Culprit Surprises E...

Agitation in Alzheimer’s Dementia
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Agitation in Alzheimer’s Dementia

U.S. Bombers Strike IJN Carrier Shōkaku: The Battle of the Coral Sea, 1942 - Animated
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U.S. Bombers Strike IJN Carrier Shōkaku: The Battle of the Coral Sea, 1942 - Animated

300 Secret Historical Photos You Were Never Supposed to See
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300 Secret Historical Photos You Were Never Supposed to See

Why You Can’t Sleep (and How to Fix It) |  Dr. Michael Grandner
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Why You Can’t Sleep (and How to Fix It) | Dr. Michael Grandner

You Can Prevent Alzheimer’s: The New Science of Brain Health
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You Can Prevent Alzheimer’s: The New Science of Brain Health

This Author’s New Book Has Made Trump SUPER Mad
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This Author’s New Book Has Made Trump SUPER Mad

‘Trump Is the Worst Symptom’ Progressive Democrat Brutally Roasts Trump in Fiery Speech
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‘Trump Is the Worst Symptom’ Progressive Democrat Brutally Roasts Trump in Fiery Speech

A shocking find in stump in a cemetery
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A shocking find in stump in a cemetery

11 Symptoms of Dangerous B12 Deficiency (Even If Tests Say You’re Fine)
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11 Symptoms of Dangerous B12 Deficiency (Even If Tests Say You’re Fine)