Treatment-Resistant Depression? Why Doctors Skip MAOIs

https://notonanemptymind.thinkific.com for more great, exclusive content! Register as a prospective student at my online academy free of charge or obligation to receive special notices and offers. An Overview of the MAOIs: monoamine oxidase inhibitors phenelzine (Nardil), tranylcypromine (Parnate), isocarboxazid (Marplan), and selegiline (EMSAM, Eldepryl). Despite long washout periods when starting or stopping these agents, low-tyramine diet requirements, multiple daily doses and the possibility of hypertensive crises and serotonin syndrome if taken improperly, combined with the wrong medications (including several over-the-counter preparations) or a tyramine-rich diet, as a class the MAOIs are probably the most effective antidepressants, and are often overlooked when patients suffering from refractory (treatment-resistant) major depressive disorder are referred for an evaluation to undergo ECT (electroconvulsive therapy).