Why Physical AI Is the Next Big Opportunity | Deep Dives with a16z
Erin Price-Wright speaks with Alex Modon, cofounder and CEO at Unlimited Industries, and Davide Asnaghi, CEO at Diode Computers, about how AI is moving from software into the physical world. They discuss automating construction and electronics design, using code and simulation to model real-world systems, and how incentives and manufacturing constraints shape adoption. They also examine what it takes to scale infrastructure, reduce build times, and unlock more abundant industrial capacity in the United States. Timestamps: 00:00 - Trailer 00:51 - Introductions & What is Physical World AI 02:00 - Automating Construction End to End 04:36 - Automating Circuit Board Design & Manufacturing 10:16 - Changing Entrenched Industries & Vertical Integration 19:21 - Getting AI to Understand Real World Physics 29:28 - Do We Need a Breakthrough to Close the Last Gap? 34:24 - Humanoids, Robotics & the Future of Physical Automation 44:54 - Second Order Effects & Why This Work Matters Read the full transcript here: https://www.a16z.news/s/podcast Resources: Follow Alex on X: https://x.com/alexmodon Follow Davide on X: https://x.com/davideasnaghi Follow Erin on X: https://x.com/espricewright Stay Updated: If you enjoyed this episode, be sure to like, subscribe, and share with your friends! Find a16z on X: [https://x.com/a16z](https://x.com/a16z) Find a16z on LinkedIn: [ / a16z ]( / a16z ) Listen to the a16z Podcast on Spotify: [https://open.spotify.com/show/5bC65RD...](https://open.spotify.com/show/5bC65RD...) Listen to the a16z Podcast on Apple Podcasts: [https://podcasts.apple.com/us/podcast...](https://podcasts.apple.com/us/podcast...) Follow our host: [https://x.com/eriktorenberg](https://x.com/eriktorenberg) Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see [a16z.com/disclosures](http://a16z.com/disclosures).

Why the next AI boom is physical AI | Caitlin Kalinowski (ex-OpenAI, Meta, Apple)

The $15B Physical AI Company: Simulation, Autonomy OS, Neural Sim, & 1K Engineers—Applied Intuition

My AI Sent 10,000 Emails — By Mistake

World's Top Researcher on AI, LLMs, and Robot Intelligence

Demis Hassabis: We're Three Quarters of the Way to AGI

MIT’s Russ Tedrake Says Robotics Is Finally on a Rocket Ship

Leading in the Age of AI: A Conversation with NVIDIA CEO Jensen Huang | Global Conference 2026

What is Physical AI? How Robots Learn & Adapt in Real Life

Pyramid of Work and The Future of Enterprise Automation | The a16z Show

The Founder Using Claude to Build Real Hardware

The Hardest Problem AI Ever Solved, with Google DeepMind CEO

This is AGI: Sequoia AI Ascent 2026 Keynote

Ken Goldberg: Good Old-Fashioned Engineering Can Close the 100,000 Year “Data Gap” in Robotics

Andrej Karpathy: From Vibe Coding to Agentic Engineering w/ Stephanie Zhan

The New Rule for Picking AI Winners | The a16z Show

Demis Hassabis: Agents, AGI & The Next Big Scientific Breakthrough

The AI Skills Nobody is Teaching (And Everyone Needs) | AI Expert Ethan Mollick

Demis Hassabis: Why AGI is Bigger than the Industrial Revolution & Where Are The Bottlenecks in AI

The Two Harvard Dropouts Who raised $800M to take on NVIDIA

