340B GPO Prohibition Court Ruling: WAC Purchasing & Compliance for Hospital Pharmacies | IGQ Ep. 2

Has the recent 340B GPO Prohibition Court Ruling changed how hospital pharmacies should manage WAC purchasing, 340B compliance, and inventory replenishment strategies? In Episode 2 of the I Got Questions (IGQ) Podcast, host Jason Mills welcomes 340B expert Kyle Lenio to unpack one of the most talked-about developments in the hospital pharmacy supply chain this year. Together, they break down the court decision challenging HRSA's guidance around the 340B GPO Prohibition, explain what was actually challenged, and discuss what the ruling means for hospital pharmacy operations, purchasing strategies, inventory management, and compliance programs moving forward. In this episode, we discuss: What the 340B GPO Prohibition actually says—and what the court ruling did (and did not) change Why WAC purchasing remains a critical component of 340B inventory management How hospitals can think strategically about initial drug purchases under the new ruling The impact of drug shortages on WAC spend and pharmacy purchasing decisions Opportunities for GPOs, manufacturers, and hospitals to reduce unnecessary WAC premiums Specialty pharmacy considerations and high-cost medication purchasing strategies Practical compliance considerations for hospital pharmacy leaders and buyers Episode Chapters: 00:00 – Welcome to the IGQ Podcast: Introduction to Kyle Lenio and the 340B GPO Prohibition Court Case 02:53 – Understanding the 340B GPO Prohibition and Drug Purchasing 05:00 – Lawsuit Challenging HRSA Guidance: The Replenishment Model and Initial Purchases 07:45 – The Court Case: What Was Actually Challenged? 08:47 – Initial Reactions and Potential Operational Impact 10:02 – How Split-Billing and Replenishment Models Could Change 11:57 – Is the Initial WAC Purchase Really a Problem? 12:35 – Implications for High-Waste Products 13:43 – Why GPOs Care About WAC Volume 16:24 – Could Manufacturers and GPOs Work Together to Alleviate Hospital Spend? 19:35 – Common Misconceptions About the 340B GPO Prohibition Court Ruling 20:13 – Audits, Compliance, and Hospital Risk Considerations 20:54 – High-Cost Drug Purchasing and Acquisition Cost: Could States Make a Case? 24:57 – Implications for Specialty Pharmacies 26:32 – Should WAC Accounts and the GPO Prohibition Be Revisited? 29:05 – Insulins, OR Drugs, Drug Shortages, and Reclassification Challenges: How to Avoid High WAC Premiums 32:49 – Final Thoughts and Closing Discussion 34:16 – Outro About the IGQ Podcast: Hosted by QuicksortRx pharmacist Jason Mills, IGQ brings industry experts together to explore the special nuances in the pharmacy industry. Our goal is to provide smart, intentional, and relatable insights for pharmacy leaders navigating a modern healthcare landscape. Learn more about optimizing your pharmacy spend at: https://quicksortrx.com/ #340B #HRSA #PharmacyProcurement #WACPurchasing #PharmacyLeadership #IGQPodcast