GLP-1s Through a GI Doc’s Eyes: What Happens From Bite to Butt

Bloating, bathroom drama, and the science that actually matters. Ozempic, Wegovy, Mounjaro, Zepbound - millions are taking them. But what are they really doing from esophagus to colon? In this episode of Get the Skinny, I sit down with a board-certified gastroenterologist to break down what GLP-1s do from esophagus to colon: delayed gastric emptying (in plain English), constipation vs diarrhea, gallbladder risk, microbiome shifts, and whether these meds help or harm fatty liver. We also talk “food noise,” prescribing ethics, and the #1 daily habit your gut wishes you took seriously! 🎙 Hosted by: Zach Jacobs — Founder, Jurni GLP (currently on Wegovy 0.25MG) 👩‍⚕️ Guest: Dr. Strick Woods — Gastroenterologist, Connecticut 1:47 - What was happening to my body in that moment? 03:09 - Have you seen an uptake in your practice with the introduction of GLPs? 3:41 - When did you see the uptake in patients listing GLP's on their intake documents? 04:02 - Do you have any Pros or Cons on the GLP-1s ? 04:36 - Have as a gastroenterologist ever coached people on lifestyle changes? 05:25 - Delays gastric emptying - What does this mean in plain English? 06:32 - Is Gastroparesis the same thing as delayed gastric emptying? 07:20 - Why do some people get constipated vs. some getting diarrhoea? 08:14 - Does hydration have any effect on constipation or diarrhoea? 08:58 - How does fiber play into the equation? 09:55 - What's the perfect bowel movement? 12:52 - What are some current GI conditions that the GLP-1s are starting to affect? 14:00 - Are you aware of any positive effects the GLP-1s are having on the fatty liver? 14:38 - Does rapid weight loss increase the risk of gallbladder and gallstones? 15:37 - Are you seeing meaningful lasting shifts in the microbiome? 16:28 - Are gastroenterologists able to prescribe GLP-1 medications? 17:31 - Could you please bifurcate general inflamation reduction and fatty liver? 19:12 - How much research do you do before prescribing new medications? 20:13 - Have you ever heard of the term food noise? Do you see the GLP-1 more as a gut/brain hybrid drug? 21:14 - What's one thing you wish everyone understood better about their gut? 21:51 - Is there a simple daily habit you wish people took more seriously for gut or digestive health? 22:16 - Is there a go to vegetable in your household? 22:34 - Have you ever seen a medication affect positively so many aspects of the digestive system? 23:43 - How did your point of view change regarding the GLP-1s in comparison to 3 years ago? #GLP1 #GLP1Community #Ozempic #Wegovy #Mounjaro #Zepbound #GetTheSkinny #ZachJacobs #WeightLossDrugs #DoctorInterview #HealthPodcast #Fact #Science #Advice #Gastroparesis #Microbiome #FattyLiver #NAFLD #Gallstones #FoodNoise"