Simulation #268 Dr. George Church - Synthetic Biology

Dr. George Church is a Geneticist, Molecular Engineer, and Chemist. He's been a Professor at Harvard & MIT for 33 years and runs the 100 person Church Lab. He's co-founded 22 companies, co-authored 500 papers, has 143 patent publications, and is the author of Regenesis. http://arep.med.harvard.edu https://en.wikipedia.org/wiki/George_... Regenesis ► http://bit.ly/SimRegenesis SHOW NOTES 📝 0:00 Welcome, introduction, Dr. Church CV 1:30 Tweaking biology with a 30,000-foot view of history 3:01 "Point of awe" discussion; species extinction, DNA, and carbon sequestration 5:01 X-ray crystallography breakthrough conversation 7:18 Genome sequencing; founding early companies; data interoperability via blockchain 10:31 More on privacy and access controls; UBI mention; data silo and homomorphic encryption 13:12 CRISPR/Cas9 conversation; "eighth wave"; picking the best sequencing 15:53 TAL still in use; next-generation target is multiple sites at once; off-target and on-target, avoiding off-target 18:31 Use of computational biology in genetic engineering; inspiration of outliers 20:14 Vaccine and cognitive enhancement conversation 22:35 Neuroplasticity and neurodegeneration importance; MICrONS Project reference, reconstructing connectomes 25:38 Importance of knowledge preservation; "it takes a lifetime to get to a point of competence"; reversing the planned obsolescence of aging by actually staying younger 29:12 More on longevity and Dr. Church's work at the Wyss Institute; "atomically precise engineering at scale" 33:58 Managing a 100+ person lab and design conversation; failing fast, groups of three, interdisciplinary teams; importance of both co-mentorship and entrepreneurship 38:28 Keeping up with all the scientific developments 40:10 Information dissemination in the lab and educating the general public; pgED.org mention 42:53 Workflow design in the lab; alumni network, principle of patience 44:50 Simulation Q1: What is a core driving principle in your life? 46:30 Simulation Q2: Do you think we live in a simulation? 47:25 Simulation Q3: What is the most beautiful thing in the world? 48:26 Thanks and appreciation, closing comments Welcome ✌🏽 We Uncover The Nature of Reality 1 Interview Smart People 2️ Synthesize First Principles 3️ Elevate Planetary Consciousness ⭐ http://simulationseries.com 🧬 Find Us Everywhere YouTube ► http://bit.ly/SimYoTu 👀 SOCIAL Instagram ► http://bit.ly/SimulationIG Twitter ► http://bit.ly/SimulationTwitter Facebook ► http://bit.ly/SimulationFB LinkedIn ► http://bit.ly/SimulationLinkedIn Telegram ► http://bit.ly/SimulationTG 🎧 AUDIO iTunes ► http://bit.ly/SimulationiTunes Spotify ► http://bit.ly/SpotifySim SoundCloud ► http://bit.ly/SimulationSC Insight Timer ► http://bit.ly/SimInsight 💰SUPPORT PayPal ► http://bit.ly/SimPayPal Patreon ► http://bit.ly/SimulationPatreon Crypto ► http://bit.ly/CryptoSimu 🇨🇳 CHINA BiliBili ► http://bit.ly/SimBiliBili 👕 MERCH Yoobe ► https://yoobe.me/simulation 🎤 PUBLIC SPEAKING All Videos ► https://allensaakyan.com TEDx Talk ► http://bit.ly/AllenTEDx Questioning Growth ► http://bit.ly/QuestioningGrowth 1,000 Robotics Students ► http://bit.ly/AllenFIRST Instagram ► http://bit.ly/AllenIG Twitter ► http://bit.ly/AllenT ❓ QUESTIONS 📹 HIRING List ► http://simulationseries.com/the-list Email ► [email protected]