"Coffee" with a Clinician March 11: Post-Exertional Malaise (PEM), part 1

Clinical Care Guide Chapter 4: Post-Exertional Malaise, Sections 4.1 and 4.2 - Key characteristics and pathophysiology of post-exertional malaise (PEM) In this March “Coffee” with a Clinician session, experts break down the key characteristics and underlying biology of PEM, drawing from Chapter 4 of the Clinical Care Guide: Managing ME/CFS, Long COVID & IACCs. You’ll hear from: Larry Baldwin, MD – Researcher and person living with ME/CFS Staci Stevens – Exercise physiologist and co-founder of Workwell Foundation Clayton Powers, DPT – Education Liaison at Bateman Horne Center (moderator) Together, they explore: What makes PEM different from normal fatigue Why symptoms are often delayed (12–72 hours) after exertion How PEM affects multiple systems (cognitive, autonomic, immune, and more) What current research suggests about energy metabolism and neuroimmune dysfunction Why PEM is not deconditioning—and how testing like the 2-day CPET helps demonstrate this Practical ways to recognize your personal PEM time course and support pacing This session also highlights emerging research, ongoing challenges in diagnosis, and the importance of education for both patients and providers. This session is part of our ongoing series that explores the Bateman Horne Center Clinical Care Guide chapter by chapter, offering evidence-informed education to support patients, clinicians, and caregivers. Disclaimer: This presentation is for educational purposes only and does not constitute medical advice. Explore the Clinical Care Guide: https://batemanhornecenter.org/clinic... Transcript: https://batemanhornecenter.org/wp-con... Presenter Slides: https://batemanhornecenter.org/wp-con... ☕ “Coffee” with a Clinician is a free monthly series made possible by donor support, helping expand education and access to care for people living with ME/CFS, Long COVID, and related conditions. Video description generated by AI from session transcript.