Non Steroidal Anti-inflammatory Drugs|| Pharmacology Chapter 2 part 9 (#NSAIDs) #aspirin

SR Pharmacy App Link : https://vbclnx.on-app.in/app/home?org... Join My Telegram Channel https://t.me/S_R_Pharmacy_Official Follow me on instagram   / s_r_pharmacy   My Facebook Page   / 1zfn3qvkav   Whatsapp Channel Join Now https://whatsapp.com/channel/0029VaEh... In this video we study about #Non_Steroidal_Anti_Inflammatory_Drugs ( #NSAIDs) The drugs are used to treat Inflammation , and mild to moderate Pain and fever are called Non steroidal anti Inflammatory drugs . Inflammation : It is a condition in which part of the body becomes reddened , swollen , hot, and painful , especially as a reaction to injury or infection . #Classification_of_Non_Steroidal_Anti_Inflammatory_Drugs (NSIADs) 1) Non -Selective COX inhibitors a) Salicylates : Aspirin b) pyrazolone Derivatives : Phenylbutazone c) Indole Derivatives : Indomethacin d) Propionic Acid Derivatives : Ibuprofen e) Aril Acetic Acid Derivatives : Diclofenac f) oxycame Derivatives : Piroxicam #Indications_Non_Steroidal_Anti_Inflammatory_Drugs 1) #Analgesia : NSIADs are used to eliminate or treat mild to moderate pain like : a) headache b) toothaches c) muscle aches d) arthritis e) migraine f) Dysmenorrhea 2) #Antipyresis : NSIADs are used to treat fever / to normalize body temperature . 3) Anti Inflammation : NSIADs are used to stop inflammation and pain like : a) Rheumatoids b) osteoarthritis c) Ankylosing spondylitis d) bursitis #Adverse_Effects_Non_Steroidal_Anti_Inflammatory_Drugs 1) In Stomach : NSIADs block the biosynthesis of PG ( prostaglandins ) , which inhibit the acid secretion and promote the secretion of cytoprotective mucus in the GIT . If these PGs are inhibited there are more chances to damage the inner layer of stomach , and may cause the gastric ulcer . 2) In Platelets : The function of platelets are disturbed because NSIADs prevent the formation of TXA2 ( thromboxane A2 ) , which helps in blood clotting . 3) In Uterus : prostaglandins help to open the cervix because of contraction , but in the case of inhibition of PGs cause difficulty in labor .(child birth ) 4) In Kidneys : NSIADs decrease the renal blood flow and the glomerular filtration rate . #Contraindication_Of_Non_Steroidal_Anti_Inflammatory_Drugs 1) with NSIADs hypersensitivity ( an exaggerated response by immune to a drug ) . 2) In peptic Ulcer , 3) In children suffering from chicken pox or influenza . 4) In chronic liver disease 5) In during pregnancy . 6) in breastfeeding mother . Detail study of some drugs 1) Aspirin : It is a non selective anti- inflammatory drug . #Non_Steroidal_Anti_Inflammatory_Drugs_by_srpharmacy #srpharmacy ‪@srpharmacy‬