Exxua Deep, Deep Dive: The Complete Pharmacological Breakdown
https://notonanemptymind.thinkific.co... Take a deep, DEEP dive into the azapirone class of psychotropic agents: gepirone (Exxua) and buspirone (Buspar). Or, check out the abridged version of this video in this playlist! 00:00 Intro 01:34 Buspar (buspirone) 02:01 Selectivity (SSRIs) 02:58 Viibryd (vilazodone) 3:33 Gepirone: clinical pearls 04:08 QT Prolongation 05:30 Common Side Effects 05:49 Sexual Dysfunction 06:31 Pediatric Use/Pregnancy 07:33 Summary 08:25 Gepirone's Niche: Anxious Depression 09:11 Exxua vs. Buspar 09:44 Co$t 10:11 Buspar and Dopamine 10:58 5-HT (Serotonin) 12:16 Full Agonist? 12:58 The Synapse 13:22 Autoreceptors: Negative Feedback 14:30 Heteroreceptors 15:58 Dorsal Raphe Nucleus (DRN) 17:11 Full vs. Partial Agonism 18:14 Net Physiological Effects 22:45 Too Much or Too Little? 24:44 Autoreceptor Desensitization 27:54 Clinical Implications
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