NEW & HOT in Korean Skincare? 🩺 PDRN: Here's What No One Is Telling You 🧴 Serums and Injectables 🩼

NOT SPONSORED Is PDRN actually worth it? Korean beauty's lateset! As a doctor, I read the papers so you don't have to. In this video I break down exactly what PDRN (polydeoxyribonucleotide) is, how it works, what the evidence really says about injectables vs topical serums — and whether anything can beat SPF and retinol for anti-aging. No sponsorship, just the science. 🍿Watch next SNAIL MUCIN: Science, Routines and COS Rx 96 Power Essence:    • SNAIL MUCIN: Science, Routines and COS Rx ...   LED Masks:    • DO LED MASKS work for ACNE, WRINKLES, FINE...   🔗 Links Look Fantastic 20% off code: LFTFDRSAPNA https://tidd.ly/3u8NXIN Medicube PDRN Pink Peptide Serum 30ml https://tidd.ly/42le7pf Lancôme Absolue Soft Cream 60ml https://tidd.ly/4uLYBPo Anua: PDRN Hyaluronic Acid 100 Moisturising Cream 60ml https://tidd.ly/4tjOsrW Anua Azelaic Acid 10 Hyaluron Redness Soothing Serum 30ml https://tidd.ly/3Puxqtn 📚CHAPTERS 00:00 Intro 00:16 What is PDRN? 01:15 How Does PDRN Work? 02:15 Benefits of PDRN 02:53 Injectable PDRN 04:01 Who Benefits from PDRN? 05:03 PDRN Research & Data 08:54 Topical PDRN 10:20 Medicube PDRN Review Pink serum! 13:54 Injectable Brands 13:54 Cons of PDRN 16:09 Final Thoughts 📊 REFERENCES 1. Arora G. Polynucleotides and polydeoxyribonucleotides in dermatology — a narrative review. J Cutan Aesthet Surg. 2026;19:17–28. doi:10.25259/JCAS_65_2025 https://jcasonline.com/polynucleotide... 3. Galeano M, Pallio G, Irrera N, et al. Polydeoxyribonucleotide: a promising biological platform to accelerate impaired skin wound healing. Pharmaceuticals (Basel). 2021;14(11):1103. https://pmc.ncbi.nlm.nih.gov/articles... 4. Kim HM, Byun KA, Oh S, et al. A mixture of topical forms of polydeoxyribonucleotide, vitamin C, and niacinamide attenuated skin pigmentation and increased skin elasticity. Molecules. 2022;27(4):1276. https://pmc.ncbi.nlm.nih.gov/articles... 5. Kim YJ, Kim MJ, Kweon DK, et al. Polydeoxyribonucleotide activates mitochondrial biogenesis but reduces MMP-1 activity and melanin biosynthesis in cultured skin cells. Appl Biochem Biotechnol. 2020;191(2):540–54. https://pubmed.ncbi.nlm.nih.gov/31811... 6. Lampridou M, et al. The effectiveness of polynucleotides in esthetic medicine: a systematic review. J Cosmet Dermatol. 2024. doi:10.1111/jocd.16721 https://pubmed.ncbi.nlm.nih.gov/39645... 7. Lee JH, et al. Comparison of polynucleotide and polydeoxyribonucleotide in dermatology: molecular mechanisms and clinical perspectives. Pharmaceutics. 2025;17(8):1024. https://pmc.ncbi.nlm.nih.gov/articles... 8. Pittayapruek P, Meephansan J, Prapapan O, et al. Role of matrix metalloproteinases in photoaging and photocarcinogenesis. Int J Mol Sci. 2016;17(6):868. https://pmc.ncbi.nlm.nih.gov/articles... 9. Points to ponder on the role of polynucleotides in regenerative and aesthetic medicine: a systematic review. Eur J Plast Surg. 2024. doi:10.1007/s00238-024-02209-x https://link.springer.com/article/10.... 10. Squadrito F, Bitto A, Altavilla D, et al. The effect of PDRN, an adenosine receptor A2A agonist, on the healing of chronic diabetic foot ulcers. J Clin Endocrinol Metab. 2014;99(5):E746–53. https://pubmed.ncbi.nlm.nih.gov/24483... 11. Squadrito F, Bitto A, Irrera N, et al. Pharmacological activity and clinical use of PDRN. Front Pharmacol. 2017;8:224. https://pmc.ncbi.nlm.nih.gov/articles... 12. Xu C, Wang L, Fozouni P, et al. SIRT1 is downregulated by autophagy in senescence and ageing. Nat Cell Biol. 2020;22(10):1170–9. https://pmc.ncbi.nlm.nih.gov/articles...