The Aging Kidney with Dr Andrew Rule

Dr. Andrew Rule After receiving his B.S. in Bioengineering and his M.D. from University of Washington in 1999, Dr. Andrew Rule completed residency in internal medicine and fellowship in nephrology at the Mayo Clinic in 2006. He subsequently stayed on staff at the Mayo Clinic as an academic nephrologist. His early career was launched with several seminal contributions in estimating glomerular filtration rate (GFR) with serum creatinine and cystatin C. Subsequently he developed and led the multi-center Aging Kidney Anatomy study that since 2010 has studied structure-function-outcome relationships in the kidneys of living kidney donors and in patients who undergo nephrectomy for tumors.  His research program then expanded to long-term outcomes of living kidney donors compared to well-matched controls (MARK-D study) and most recently a population-based study of deep learning derived organ and tissue measures for accelerated aging using repurposed abdominal CT images (REP-CT study).  He also serves as the Nephrology Section Editor for the Mayo Clinic Proceedings. He was nominated into membership at the American Society for Clinical Investigations in 2019. Dr. Rule publishes about 25 papers per year and has obtained an h-index of 68 and an i10-index of 183 (Google Scholar). Learning Objectives: To review the structural and functional changes in the kidney with aging To understand the implications of kidney aging in the diagnosis of chronic kidney disease