Hallmarks of Cancer Part 3 | Resisting Cell Death, Warburg Effect & Replicative Immortality
Cancer cells don't just grow rapidly—they also develop unique abilities that help them survive and multiply indefinitely. In this video, based on the latest Robbins & Cotran Pathologic Basis of Disease, we discuss three important hallmarks of cancer: Resisting Apoptosis (Evading Programmed Cell Death) Altered Cellular Energy Metabolism (Warburg Effect) Enabling Replicative Immortality (Role of Telomerase) 00:00 Introduction 01:21 Resisting Apoptosis 12:10 Warburg Effect 21:42 Autophagy 24:02 Oncometabolism 27:35 Enabling replicative immortality 32:08 Self renewal This lecture covers: Intrinsic and extrinsic apoptosis pathways BCL-2 family proteins, p53, and caspases Warburg effect and metabolic reprogramming in cancer Aerobic glycolysis and its advantages for tumor cells Telomeres and telomerase Cellular senescence vs immortality Clinical significance and targeted therapies High-yield concepts for MBBS, MD Pathology, NEET PG, INI-CET, FMGE, and university examinations If you found this lecture helpful, please Like, Share, Subscribe, and press the notification bell for more pathology lectures. #HallmarksOfCancer #CancerBiology #RobbinsPathology #Apoptosis #WarburgEffect #Telomerase #ReplicativeImmortality #Pathology #MBBS #MDPathology #NEETPG #INICET #FMGE #MedicalEducation #MedicalStudents #PathoInsights #Oncology #PathologyLecture #Cancer #DrNeyaz
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