Oral SERDs Explained: A New Option for Breast Cancer Patients

Oral selective estrogen receptor degraders (SERDs) are reshaping hormone receptor-positive (HR+) metastatic breast cancer treatment. Could they replace fulvestrant? Dr. Francisco J. Esteva explains the science, key clinical trials, and what these advances mean for patients and oncologists. #cancer #cancertreatment #breastcancer Chapters: 0:00 Introduction 01:58 Fulvestrant: first SERD 02:22 Elacestrant: first oral SERD approved 02:36. Liquid biopsy to detect mutant ESR1 03:35 SERENA-6 trial: camizestrant in first line MBC 05:05 Conclusions About Dr. Esteva Francisco J. Esteva, MD, PhD is a medical oncologist based in New York with a specialization in breast cancer. He completed an Oncology Fellowship at Georgetown University Hospital and an Internal Medicine Residency at Cooper Medical School of Rowan University. Dr. Esteva serves as Division Chief at Lenox Hill Hospital and has previously held faculty appointments at NYU and The University of Texas MD Anderson Cancer Center. He has authored numerous peer-reviewed publications and has led more than 100 clinical trials focused on breast cancer treatment, diagnostics, and predictive biomarkers. His honors include Fellowship in the American College of Physicians, election to the American Society for Clinical Investigation, the 2019 Physician of Impact Award from Susan G. Komen NYC, and election to the NYC American Cancer Society Board of Advisors in 2024. Medical Disclaimer The content in this video is intended for informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek guidance from your physician or another qualified health professional regarding any medical condition. Do not disregard professional medical advice or delay seeking care because of information presented in this video. The views shared in this video represent Dr. Esteva’s personal opinions and do not reflect those of his employer. Non-Sponsorship & Affiliation Disclaimer This video is not sponsored. Any mention of products, medications, or brands is for educational purposes only and does not imply endorsement. Advertisements that may appear are placed by YouTube; I am not affiliated with, nor do I endorse, any advertised products or services.