Fireside Chat with Nemil Dalal (Y Combinator) and Kartik Talwar (ETHGlobal) at ETHConf

In this fireside chat, Kartik Talwar sits down with Nemil Dalal, visiting partner at Y Combinator and former head of Coinbase's developer platform, to discuss the early days of USDC, the current state of crypto startups, and what YC is looking for from founders. Nemil walks through how he spent seven years at Coinbase leading USDC from launch in 2018, when many in crypto circles thought stablecoins were the wrong vision and Bitcoin should replace everything. He pushed against two early strategies that didn't fit Coinbase's positioning as a US based regulated company: chasing high yield Asian markets where Tether dominated, and selling to banks that only knew about Bitcoin and saw stablecoins as a beta dollar. The breakthrough insight was bootstrapping DeFi adoption through the USDC Bootstrap Fund, deploying capital into Uniswap, Aave (then EthLend), DyDx, and other early protocols. Nemil shares how YC funds about 100 crypto startups today and expects to 10x that in the next decade, since crypto is moving from a niche DGen product to something most Americans will use without realizing. He outlines what YC is excited about: stablecoins and the businesses built on top, tokenized assets including equities and debt, and AI plus crypto including X2X (which Nemil's team launched at Coinbase). He shares his controversial view that founders should launch fewer tokens, since most are incentive tokens that act like marketing schemes attracting mercenary users and worsening UX, while reserving tokens for L1s, L2s, and DeFi protocols where decentralization is genuinely core to the product. On regulation, he tells the story of Coshi spending three years suing the CFTC and winning, framing regulation as either go regulation forward and specialize per country, or follow the Binance playbook offshore first. He closes urging founders to combine crypto with AI thoughtfully and pointing to the rolling YC application deadline. 00:00 Introduction 00:08 Nemil's Background and Homecoming to Ethereum 01:08 Launching USDC at Coinbase in 2018 02:26 Why Stablecoins Were Controversial in Crypto Circles 02:41 Two Bad Early Strategies: Asia Yield and Banks 03:41 The Breakthrough: Bootstrapping DeFi 03:58 Maker DAO, Compound, and Early DeFi Signals 04:23 Launching the USDC Bootstrap Fund 05:10 Nemil's Role as Visiting Partner at Y Combinator 05:38 What YC Offers Founders 06:20 Funding 100+ Crypto Startups and 10x'ing the Pace 07:00 Why Bear Markets Are the Best Time to Build 07:32 Tourists vs Real Builders 07:50 Why ETH Global Hackathon Attendance Correlates Inversely with Price 08:46 What YC Is Looking to Fund in 2026 09:04 Stablecoins and Stablecoin Neo Banks 09:51 Tokenized Stocks, Debt, Equity, and Emerging Markets 10:12 X2X and the AI Plus Crypto Opportunity 10:50 Agentic Finance May Be Agnostic to Crypto vs Credit Cards 11:33 YC's Mindset: Make Something People Want 12:14 Where Is the Saturated Space in Crypto Startups 12:38 Common Patterns: Dev Tools, On Off Ramps, Wallets 13:08 Prediction Markets and Crypto as Core Stack 13:25 Should Founders Launch a Token 14:10 Incentive Tokens as a Marketing Scheme 14:48 Tokens Often Hurt User Experience 15:19 Where Tokens Genuinely Make Sense: L1s, L2s, DeFi 16:05 Solving Pain Points, Not Decentralizing for Its Own Sake 16:36 How Founders Should Think About Regulation 17:01 The Coshi Story: Suing the CFTC and Winning 17:39 Regulation Forward vs Binance Playbook 18:43 Onshore vs Offshore Based on Product Type 19:00 How to Apply to YC and Reach Nemil 19:35 The Magic of Crypto and AI Coming Together 20:33 Closing _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ ETHConf 2026 ETHConf is a 3 day event for founders, industry leaders, and builders who are excited about the possibilities of building on top of Ethereum. Connect with 2,000+ top innovators in crypto, finance, technology, and policy at our inaugural three-day event packed with showcases, demos, partnerships, and conversations shaping the future of the global economy. _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ ✅ Follow ETHConf X: https://x.com/ethconf Website: https://ethconf.com _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ 🎟️ Get your early bird tickets for ETHConf 2027: https://ethconf.com/2027#tickets 🎤 View the full ETHConf 2026 Speaker Schedule: https://ethconf.com/schedule _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _