Toxicology: Alcohols, Opioids, Antidotes & Salicylates | EM Board Review

Critical toxidromes and antidotes. Opioid toxicity with ventilation first, toxic alcohols (methanol, ethylene glycol, isopropanol) and fomepizole, acetaminophen overdose and the Rumack-Matthew nomogram, salicylate toxicity and intubation danger, calcium channel blocker and beta-blocker overdose, sodium channel blockade and bicarbonate, and digoxin toxicity with Fab fragments. 📑 Chapters 0:00 Intro 0:03 Title 0:25 Objectives 0:58 ED Mindset ABCs & Glucose First 1:23 Toxidromes Pattern Recognition 2:41 Opioid Toxicity Ventilation First 3:13 Naloxone Dosing & Strategies 4:10 Toxic Alcohols Lab Pattern 5:20 Toxic Alcohols Lab Pattern pre aniongap splice 6:29 Toxic Alcohols Lab Pattern pre iso splice 7:39 Toxic Alcohols Lab Pattern pre splice 8:48 Toxic Alcohols Lab Pattern pre userSplice 9:58 Toxic Alcohols Lab Pattern spliced backup 11:08 Fomepizole & Dialysis 11:59 Acetaminophen Overdose & NAC 13:11 Salicylate Toxicity & Bicarbonate 14:24 Calcium Channel & Beta Blocker Overdose 15:37 Sodium Channel Blockade TCA & Cocaine 16:40 Digoxin Toxicity & Fab 17:47 Toxicology Board Traps 18:28 Case 1 Methanol Visual & Acidosis 18:59 Case 2 Salicylate & Intubation Risk 19:33 Board Question 1 19:51 Board Question 2 20:09 Board Question 3 20:28 Final Takeaways 21:06 Final Takeaways KEEP 21:45 References Presented by Ezekiel Shepard, M.D. Shepard EM Board Review — high-yield emergency medicine education for board exams, shift performance, and clinical reasoning. ⏱ CHAPTERS 0:00 Title 0:20 Objectives 0:58 ED Mindset ABCs and Glucose First 1:25 Toxidromes Pattern Recognition 2:29 Opioid Toxicity Ventilation First 3:03 Naloxone Dosing and Strategies 3:54 Toxic Alcohols Lab Pattern 4:46 Fomepizole and Dialysis 5:44 Acetaminophen Overdose and NAC 6:43 Salicylate Toxicity and Bicarbonate 7:52 Calcium Channel and Beta Blocker Overdose 8:56 Sodium Channel Blockade TCA and Cocaine 9:55 Digoxin Toxicity and Fab 10:53 Toxicology Board Traps 11:39 Case 1 Methanol Visual and Acidosis 12:10 Case 2 Salicylate and Intubation Risk 12:52 Board Question 1 13:11 Board Question 2 13:33 Board Question 3 13:54 Final Takeaways 14:31 References 📚 ABOUT THIS SERIES Shepard EM Board Review delivers polished, board-relevant emergency medicine lectures for residents, attendings, and students preparing for boards or trying to sharpen on-shift clinical reasoning. Each lecture covers a focused high-yield topic with specific dosing anchors, treatment-sequence framing, and the classic board traps. 🎓 REFERENCES & ACKNOWLEDGEMENTS Content informed by Rosen's Emergency Medicine (10th edition), Foundations of EM Board Review, and current society guidelines (ACEP, AHA/ACC, SCCM, IDSA, ATLS, and others as relevant per lecture). ⚠ DISCLAIMER This content is for educational purposes only. It does not replace clinical judgment, institutional protocols, or specialty consultation. Always follow your local guidelines and consult appropriate specialists. 💬 Comment with topics you want covered next. 👍 Like and subscribe for more high-yield emergency medicine board content. #EmergencyMedicine #BoardReview #MedicalEducation #ShepardEMBoardReview