Pancreatic Cancer: 750% Increased Risk

JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT] Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2 HEALTH AUTONOMY [COURSE] Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy JOIN THE COMMUNITY Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2 EMAIL LIST 1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6 HIRE ME FOR CONSULTING: Consulting: https://bit.ly/3dmUl2H Created with Biorender 0:00 - Introduction 0:26 - It’s in your Arteries 3:02 - Is Lower Better? 6:49 - Protecting against Pancreatic Cancer 8:50 - Reverse Causality References* *Full Funding/Conflicts are provided in the free article (found in email list and Physionic Community Article Library) [Study 732] Huang X, Li H, Zhao L, Xu L, Long H. Prediabetes increases the risk of pancreatic cancer: a meta-analysis of longitudinal observational studies. PLoS One. 2024;19(10):e0311911. doi:10.1371/journal.pone.0311911 [Study 733] Cho IR, Chang SH, Lee SH, et al. Pancreatic cystic neoplasm risk among individuals with diabetes. JAMA Netw Open. 2026;9(2):e2556951. doi:10.1001/jamanetworkopen.2025.56951 [Study 734] Jee SH, Ohrr H, Sull JW, Yun JE, Ji M, Samet JM. Fasting serum glucose level and cancer risk in Korean men and women. JAMA. 2005;293(2):194-202. [Study 735] Rapp K, Schroeder J, Klenk J, et al. Fasting blood glucose and cancer risk in a cohort of more than 140,000 adults in Austria. Diabetologia. 2006;49:945-952. doi:10.1007/s00125-006-0207-6 [Study 736] Grote VA, Rohrmann S, Nieters A, et al. Diabetes mellitus, glycated haemoglobin and C-peptide levels in relation to pancreatic cancer risk: a study within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Diabetologia. 2011;54:3037-3046. doi:10.1007/s00125-011-2316-0 [Study 737] Koo DH, Han KD, Park CY. The incremental risk of pancreatic cancer according to fasting glucose levels: nationwide population-based cohort study. J Clin Endocrinol Metab. 2019;104(10):4594-4599. doi:10.1210/jc.2019-00033 [Study 738] Jacobson S, Dahlqvist P, Johansson M, et al. Hyperglycemia as a risk factor in pancreatic cancer: a nested case-control study using prediagnostic blood glucose levels. Pancreatology. 2021;21:1112-1118. doi:10.1016/j.pan.2021.05.008 [Study 739] Ke J, Lin T, Liu X, et al. Glucose intolerance and cancer risk: a community-based prospective cohort study in Shanghai, China. Front Oncol. 2021;11:726672. doi:10.3389/fonc.2021.726672 [Study 740] McDonnell D, Cheang AWE, Wilding S, et al. Elevated glycated haemoglobin (HbA1c) is associated with an increased risk of pancreatic ductal adenocarcinoma: a UK Biobank cohort study. Cancers (Basel). 2023;15:4078. doi:10.3390/cancers15164078 [Study 741] Tan PS, Garriga C, Clift A, et al. Temporality of body mass index, blood tests, comorbidities and medication use as early markers for pancreatic ductal adenocarcinoma (PDAC): a nested case-control study. Gut. Published online June 27, 2022. doi:10.1136/gutjnl-2021-326522 [Study 742] Ahn BY, Kim B, Park S, et al. Cumulative exposure to impaired fasting glucose and gastrointestinal cancer risk: a nationwide cohort study. Cancer. 2024;130:1807-1815. doi:10.1002/cncr.35197 [Study 743] Park JH, Hong JY, Shen JJ, Han K, Park YS, Park JO. Smoking cessation and pancreatic cancer risk in individuals with prediabetes and diabetes: a nationwide cohort study. J Natl Compr Canc Netw. 2023;21(11):1149-1155.e3. doi:10.6004/jnccn.2023.7060 [Study 744] Wilson RB, Lathigara D, Kaushal D. Systematic review and meta-analysis of the impact of bariatric surgery on future cancer risk. Int J Mol Sci. 2023;24(7):6192. doi:10.3390/ijms24076192 Please use the following link to submit your critique: https://bit.ly/PhysionicCritique Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.