Perioperative Cardiovascular Drug Management | Beta-Blockers, CCBs, Clonidine & POISE Trials

Management of cardiovascular drugs in the perioperative period is a critical aspect of anesthesia practice. Incorrect continuation or withdrawal of these medications can lead to serious complications such as myocardial ischemia, stroke, hypotension, and arrhythmias. DOWNLOAD APP NOW: 👉http://bit.ly/4aIWP7e 👉 http://bit.ly/4fV4nGN ☎️ Contact us: +91-7667391900 🌎 Website: www.learnanesth.com In this comprehensive video, we provide a clear, evidence-based, and exam-oriented approach to handling commonly used cardiovascular drugs during the perioperative period, along with important insights from the POISE trials. 📌 What You’ll Learn in This Video 🔹 1. Perioperative Management of Beta-Blockers Beta-blockers are widely used for hypertension, ischemic heart disease, and arrhythmias, but their perioperative management requires careful consideration. In this section, we discuss: • Whether to continue or stop beta-blockers before surgery • Risks of abrupt withdrawal (rebound tachycardia, hypertension) • Benefits in reducing myocardial ischemia • Risk of bradycardia and hypotension • Patient selection for perioperative beta-blockade • Dose titration and monitoring This is a high-yield topic for exams and clinical scenarios. 🔹 2. Perioperative Management of Calcium Channel Blockers & Clonidine This section focuses on other commonly used cardiovascular drugs: ✅ Calcium Channel Blockers (CCBs) • Role in hypertension and angina • Perioperative continuation vs discontinuation • Effects on heart rate, contractility, and vascular tone • Interaction with anesthetic agents ✅ Clonidine • Alpha-2 agonist with sympatholytic effects • Prevention of perioperative hypertension and tachycardia • Risk of rebound hypertension if stopped abruptly • Sedation and hemodynamic considerations We simplify how to balance benefits vs risks in perioperative settings. 🔹 3. POISE Trials (POISE 1, 2 & 3) The POISE trials are landmark studies that guide perioperative cardiovascular management. In this section, we cover: • POISE-1: Effects of perioperative beta-blockers (reduction in MI but increased risk of stroke and mortality) • POISE-2: Role of aspirin and clonidine in non-cardiac surgery • POISE-3: Blood pressure management strategies and anticoagulation considerations