The Schizophrenia Puzzle is Solvable | W. Gordon Frankle, MD

There’s a care model for schizophrenia that actually works—why isn’t it everywhere? On this episode, W. Gordon Frankle, MD, MBA, Vice Chair of Psychiatry at NYU Langone Health, shares how his team in Brooklyn is building a new model for treating serious mental illness—one rooted in long-term, relationship-driven, team-based care. From wraparound services to precision psychiatry, this conversation explores what happens when you bring humanity, structure, and innovation to a population too often left behind. Dr. Frankle also discusses: • The first novel schizophrenia drug in over 50 years (Cobenfy) • Why clozapine is underused—and how that may finally change • The potential of brain imaging and biomarkers in psychiatric treatment • What a real community mental health system looks like • Why trust, not just treatment, is essential for recovery 🔍 Topics Covered:: 00:30 Introduction 01:00 Dr. Frankle’s Current Work 01:38 Advancements in Schizophrenia Research 02:59 Challenges and New Treatments in Schizophrenia 05:32 Precision Medicine in Psychiatry 06:29 PET Scans and Brain Energetics 10:16 Barriers to Effective Treatment 12:21 Clozapine and Treatment Access 14:08 Wraparound Services and Community Care 15:16 Early Screening and Public Health Interventions 19:02 Mandated Treatment and Patient Engagement 30:38 Homelessness and Mental Health 35:24 Future Directions in Schizophrenia Treatment 38:39 Conclusion 📚 Related Resources: W. Gordon Frankle, MD, MBA - https://nyulangone.org/doctors/146747... Schizophrenia care at NYU Langone - https://nyulangone.org/conditions/sch... NYU Langone Hospital—Brooklyn - https://nyulangone.org/locations/nyu-... 3 Things to Know About Cobenfy (Yale Medicine) - https://www.yalemedicine.org/news/3-t... 🙌 Support & Engage: If this episode inspired you, please like, share, and subscribe to support real conversations about transforming mental health care. 🔔 Tap the bell to stay updated on future episodes. #schizophrenia #MentalHealth #WraparoundCare #CommunityPsychiatry #Clozapine #Cobenfy #SeriousMentalIllness #PrecisionPsychiatry #NYULangone #InsightsOnPsychiatry