[메디컬 인사이트 6회] 파킨슨병의 이해와 치료법 / YTN

□ Broadcast Date: Friday, November 17, 2023, 10:20 PM □ Producers: Ji Seong-yoon, Han Taek-won □ Writers: Kim Bae-jung, Kim Hyun-jung □ Cast: Shin Hye-won (Neurologist, Chung-Ang University Hospital) □ Broadcast Channels IPTV - GENIE TV 159 / BTV 243 / LG U+ 145 Skylife 90 Cable - D'Live 138 / Hyundai HCN 341 / LG Hello Vision 137 / BTV Cable 152 The text below may differ from the actual broadcast. Please check the broadcast for more accurate information. ▶ Definition of Parkinson's Disease ▶ Symptoms of Parkinson's Disease ▶ Differences from Alzheimer's Disease ▶ Symptoms by Stage ▶ The Importance of Early Diagnosis ▶ Diagnosis Methods for Parkinson's Disease ▶ Treatment Development ▶ Limitations of Drug Treatment ▶ Deep Brain Stimulation ▶ Development of Adjunctive Therapeutics ▶ Exercise Therapy ▶ Digital Healthcare ▶ Medical AI Q&A ◆ Neurologist Shin Hye-won (hereafter referred to as Shin Hye-won): Hello. I am neurologist Shin Hye-won. Today's topic is understanding and treating Parkinson's disease. ◇ Voice Actor Park Sang-hoon: Parkinson's disease, along with dementia, is considered a representative degenerative brain disease. As our society enters a super-aging phase, the number of people seeking medical attention for Parkinson's disease is also increasing. Approximately 1.5% of the population over 60 suffers from Parkinson's disease. What are the causes and treatments for Parkinson's disease, often called another enemy of our aging society? (Definition of Parkinson's Disease) ◆ Shin Hye-won: What do you know about Parkinson's disease? If you walk with a stooped posture, drag your legs, experience tremors in your hands and feet, stiff joints, a muffled voice, and a loss of facial expression, you might suspect Parkinson's disease. Parkinson's disease was first recognized in 1817 when Dr. James Parkinson wrote an essay titled "Tremors and Paralysis," describing patients with symptoms such as hand tremors, rigidity, gait abnormalities, and stooped posture. At the time, only the symptoms were reported, so naturally, the cause of the disease was unknown. Parkinson's disease is a disease caused by the accumulation of toxic protein aggregates called Lewy bodies in the substantia nigra, a region of the midbrain where dopamine neurons are located. This accumulation destroys dopamine neurons, preventing them from functioning normally. So, what is dopamine, and what symptoms result from the loss of dopamine cells? Dopamine is one of the many neurotransmitters in the brain. Recently, interest in dopamine has grown significantly due to social issues such as gaming and drug addiction. Dopamine, associated with pleasure and addiction, acts on the limbic system, the nervous system. The dopamine neurons in the substantia nigra, which are lost in Parkinson's disease, are connected to the motor center, enabling smooth movement. Therefore, the dopamine cells lost in Parkinson's disease are responsible for motor function. Therefore, the loss of dopamine cells in Parkinson's disease leads to difficulties with smooth movement, such as slowed body movements. (Symptoms of Parkinson's Disease) ◆ Shin Hye-won: So, what does this difficulty with smooth movement mean? Let's delve deeper into the various motor symptoms of Parkinson's disease. First, bradykinesia, a reduced range of motion or slowed speed, is the most common symptom. Furthermore, in relaxed positions, such as sitting or lying down, body parts like the hands, legs, or jaw may tremble. This is called rest tremor and is a characteristic symptom of Parkinson's disease. And joint movement may be stiff and contractures may occur. Additionally, a narrow stride may occur... (omitted) Producer Han Taek-won ([email protected]) ▶ Original article: https://www.ytn.co.kr/_ln/0103_202311... ▶ Report: https://mj.ytn.co.kr/mj/mj_write.php ▣ Subscribe to YTN YouTube Channel: http://goo.gl/Ytb5SZ ⓒ YTN. Unauthorized reproduction, redistribution, and use of AI data are prohibited.