Class (04) = Acetate Pathway (Part 01) | Introduction to Acetate Mevalonate and Malonate Pathway

Download "Solution Pharmacy" Mobile App to Get All Uploaded Notes, Model Question Papers, Answer Papers, Online Test and other GPAT Materials - https://play.google.com/store/apps/de... 1. Introduction to Shikimic Acid Pathway by Solution Pharmacy in Hindi- Part I    • Class (02) = Shikimic Acid Pathway (Part 0...   2. Shikimic Acid Pathway by Solution Pharmacy in Hindi Part II    • Class (03) = Shikimic Acid Pathway (Part 0...   Introduction to Volatile Oil by Solution Pharmacy in Hindi    • Class (60) = Volatile Oil (Part 01) | Intr...   ACETATE PATHWAY 1. Acetate occupies a central position in relation to the general metabolism of plants. 2. Acetate condensation occurs in many possible routes which give rise to variety of aromatic compounds. 3. Acetic acid is the starting unit in the biosynthesis of a wide variety of straight chain and aromatic natural compounds. 4. Acetate hypothesis: building block of acetate biosynthesis is linear poly acetic chain CH3CO-(CH2-CO)n-CH2-COOH formed by repeated head to tail condensation of acetate units. 5. The discovery of acetyl CoA called Active acetate in 1950 further supported the role of acetic acid in biogenetic study. Two main route of Acetate pathway 1. Acetate Mevalonate Pathway/Isoprenoid pathway 2. Acetate Malonate pathway 1. Acetate Mevalonate Pathway/Isoprenoid pathway: Isoprenoid represent functionally and structurally the most diverse group metabolite. The “biogenetic isoprene rule” is the basis for formation of various isoprenoid compounds such as rubber, monoterpenes, sesquiterpenes, sterol, triterpenes, diterpenes Universal precursor for all isoprenoids is Isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP) and biosynthesis of these precursor takes place in mavalonic acid pathway.The 5-carbon isomers isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP) are the fundamental building blocks used to synthesize key biological isoprenoids (terpenoids) including cholesterol and other steroids, carotenoids, saponins, and limonoids. 2. Acetate malonate pathway- The main products of the acetate-malonate pathway are the fatty acids, both those primary metabolites which occur universally and the more unusual compounds with a restricted distribution. This pathway also makes an important contribution to plant aliphatic and aromatic compounds, which are biosynthesised through the formation of polyketides Get in touch with the solution by just clicking following links- Facebook Group-   / solutionpharamcy   Facebook Page-   / pharmavideo   New channel (Pharmacy Dictionary) -    / @pharmacydictionary   Instagram-   / solutionpharmacy   E-Mail for official and other work - [email protected] LinkedIn-   / pushpendrakpatel   #solutionpharmacy #Pharmacologyclass #GPATonlinetest