Dr. Greg Fahy: Thymus Regeneration & Boosting The Immune System For Longevity

Subscribe to our channel:    / @matt.kaeberlein   Dr. Greg Fahy discusses his groundbreaking research on thymus regeneration, immune system rejuvenation, and the role of growth hormone, DHEA, and metformin in reversing aging-related immune decline. He explains the TRIM protocol, the impact of thymic involution on longevity, and the potential for improving vaccine response and overall health. This conversation explores immune function, senescent cell clearance, and epigenetic aging clocks. 0:00 - Introduction & Guest Introduction 2:05 - The Origins of the TRIM Protocol 6:30 - Growth Hormone & Thymus Regeneration in Rats 12:40 - Growth Hormone, Insulin Resistance & DHEA 20:10 - Why Thymus Regeneration Matters for Longevity 27:50 - Thymic Involution & Its Role in Aging 35:45 - Measuring Thymic Function & Immune Rejuvenation 42:15 - Rapamycin, Thymus, and Immune System Enhancement 50:20 - Human Trials: Thymus Regeneration & Exercise Performance 1:03:00 - The Future of Anti-Aging & Immune Restoration Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices. More places to find us: Twitter:   / optispanpodcast   Twitter:   / optispan   Twitter:   / mkaeberlein   Linkedin:   / optispan   Instagram:   / optispanpodcast   TikTok:   / optispan   https://www.optispan.life/ Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it. On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!