Transport of Glucose, Amino Acids and Urea in Renal Tubule | Transport Maximum, Renal Threshold

📝 All videos on Renal Physiology: https://www.nonstopneuron.com/post/ph... 🌐 Explore our entire animation video library: https://www.nonstopneuron.com/ ● Follow me at: • Instagram:   / nonstopneuron   • Facebook:   / nonstopneuron   Transport of Glucose, Amino Acids and Urea in Renal Tubule | Transport Maximum, Renal Threshold: Glucose is filtered freely at the glomerulus. It is almost completely reabsorbed in the proximal tubule. The transport proteins involved… are sodium-glucose cotransporter at the apical membrane, and glucose transporter 1and2, on the basolateral membrane. Up to 200 mg/dL blood levels, glucose is not excreted in urine. This is called the renal threshold for glucose. At a filtered load of about 375 mg/min, the reabsorption reaches its maximum capacity. It is called transport maximum. Above this level, there is no further increase in glucose reabsorption, with the increase in filtration. Amino acids are also freely filtered, and almost completely reabsorbed. There are different transporters, to reabsorb different amino acids. Coming to the urea… it is reabsorbed in the proximal tubule, by solvent drag. The thin limb of the loop of Henle, secrets the urea, by the transcellular route. Then a large portion of the nephron, is impermeable. At the inner medullary collecting duct, it is reabsorbed. Finally, 40% of filtered urea is excreted in urine. Chapters: 00:00 Intro 00:19 Glucose Transport 01:45 Transport Maximum 04:07 Graph of Filtered vs Reabsorbed Glucose 05:18 Splay 05:27 Renal Threshold for Glucose 06:41 Transport Maximum in Graph 07:19 Filtered vs Excreted Glucose 08:27 Reasorption of Amino Acids 09:02 Urea Reabsorption 10:54 Factors Affecting Urea Reabsorption 11:11 Summary 12:38 Bonus Point Dr Vipul Navadiya Nonstop Neuron Medical Animation Medical Animation Videos Physiology DISCLAIMER: This video is for education purposes only. Although every effort is made to ensure the accuracy of the material, viewers should refer to the appropriate regulatory body/authorized websites, guidelines, and other suitable sources of information as deemed relevant and applicable. In view of the possibility of human error or changes in medical science, any person or organization involved in the preparation of this work accepts no responsibility for any errors or omissions, or results obtained from the use of information in this video.