Sleep 8.2 | The Suprachiasmatic Nucleus: The Body’s Central Clock

Discover how the suprachiasmatic nucleus (SCN) keeps your body on time. This video dives into the SCN’s structure, light sensitivity, and its role in synchronizing biological rhythms. Explore how melanopsin-containing retinal cells detect light, the transcription–translation feedback loop (TTFL), and the effects of artificial lighting on circadian health. We also cover the phase response curve and its clinical relevance for sleep, jet lag, and shift work. 00:00 Introduction to the Suprachiasmatic Nucleus (SCN) 01:36 SCN Synchronization Mechanisms 02:38 Intrinsic Circadian Rhythms 03:55 Role of Light in Circadian Rhythms 05:04 Impact of Modern Lighting on Circadian Rhythms 06:02 Melatonin Suppression by Light 07:50 Molecular Mechanisms of Circadian Rhythms 09:11 Phase Response Curve and Clinical Relevance *************** Start capturing high-resolution data with wearables: https://www.labfront.com Sign up for upcoming live sessions: https://lu.ma/user/usr-hqzlCBjpPnc9oBA Discover more education resources on Labfront Academy : https://www.labfront.com/academy