IPD Meta-Analysis: Two-stage or Not Two-Stage? That is the question ...

Individual participant data (IPD) meta-analysis projects must decide between a two-stage or a one-stage approach to statistical analysis, but the best approach is often debated. In this talk** I provide clear guidance for when to choose a one-stage rather than a two-stage approach, and vice versa. Findings are showcased using real examples - I hope useful! *** Talk is based on this paper: https://onlinelibrary.wiley.com/doi/1... Riley RD, et al. Two-stage or not two-stage? That is the question for IPD meta-analysis projects. Res Synth Methods. 2023;14(6):903-910. doi: 10.1002/jrsm.1661