Making and Testing The ANTI-SPICY Molecule (Capsazepine)

In this video I am making and self-testing the molecule Capsazepine (albeit crude), a molecule that blocks access to the receptor activated by the spicy-molecule capsaicin, thus removing its ability to cause you the spicy feeling. There is no known literature on its use on humans, it is used to study the TRPV1 ion-channel (spicy/heat receptor) but only in biology or biochemistry. For the azepine: https://onlinelibrary.wiley.com/doi/1... For the isothiocyanate I used a general procedure from: https://scihub.se/https://doi.org/10.... For the final coupling: https://sci-hub.se/https://doi.org/10... Check out @LabCoatz_Science who notified me of this molecule. Don't conduct any chemical reactions without proper and professional safety analysis and risk management. Measures taken can be invisible, not filmed, not properly visible on camera or misjudged by the viewer due to setup or video construction. Always conduct own appropriate measures regardless of video setup.