Backstage With: Isa Briones on ‘The Pitt,’ Playing Dr. Santos, Her Broadway Career + Actor Advice

Isa Briones sits down with Backstage to talk about her role as Dr. Trinity Santos on HBO Max’s “The Pitt,” her Broadway run in “Just in Time,” and the work that goes into balancing an acting career across television and theater. Briones shares how she auditioned for “The Pitt” while also performing in eight shows a week onstage, what medical boot camp taught her about playing a doctor, how she approached Dr. Santos’ tough exterior and vulnerability, and what it was like building her mentor-student chemistry with Noah Wyle. She also discusses advocating for her Filipino heritage, protecting personal boundaries with fans, and the advice she learned from growing up in a musical theater family.

Isa Briones Breaks Down Santos vs. Langdon & Garcia Drama | The Pitt Season 2
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Isa Briones Breaks Down Santos vs. Langdon & Garcia Drama | The Pitt Season 2

Isa Briones: Stepping Into Santos
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Isa Briones: Stepping Into Santos

Tea Time With McKenzie Kurtz
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Tea Time With McKenzie Kurtz

"The Pitt" Cast Finds Out Which Characters They Really Are
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"The Pitt" Cast Finds Out Which Characters They Really Are

The Pitt with Sepideh Moafi
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The Pitt with Sepideh Moafi

Isa Briones from "The Pitt" on playing Connie Francis in "Just In Time" on Broadway
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Isa Briones from "The Pitt" on playing Connie Francis in "Just In Time" on Broadway

This Actress Destroyed Every Autism Cliché | Acting Breakdown
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This Actress Destroyed Every Autism Cliché | Acting Breakdown

Isa Briones Had a Serious Medical Emergency While Filming The Pitt
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Isa Briones Had a Serious Medical Emergency While Filming The Pitt

The Pitt's Isa Briones and Gerran Howell on Santos and Whitaker's Unlikely Friendship
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The Pitt's Isa Briones and Gerran Howell on Santos and Whitaker's Unlikely Friendship

Isa Briones: Dr. Santos Will Be 'Reporting for Duty' for 'The Pitt' S3
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Isa Briones: Dr. Santos Will Be 'Reporting for Duty' for 'The Pitt' S3

Isa Briones Reminisces on Her Two Seasons of 'The Pitt' and What She Sees for Santos in the Future
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Isa Briones Reminisces on Her Two Seasons of 'The Pitt' and What She Sees for Santos in the Future

Fiona Dourif (The Pitt) interview with Gold Derby
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Fiona Dourif (The Pitt) interview with Gold Derby

Noah Wyle and 'The Pitt' Cast Recap Season 1 | Entertainment Weekly
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Noah Wyle and 'The Pitt' Cast Recap Season 1 | Entertainment Weekly

Joining The Cast of The Pitt | Irene Choi | Plus One
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Joining The Cast of The Pitt | Irene Choi | Plus One

Taylor Dearden on The Pitt Season 2, Response from Doctors & Going to Intense Medical Sleepaway Camp
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Taylor Dearden on The Pitt Season 2, Response from Doctors & Going to Intense Medical Sleepaway Camp

The Pitt's Isa Briones Doesn't Understand Why People Take Sides in Team Langdon Vs. Team Santos
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The Pitt's Isa Briones Doesn't Understand Why People Take Sides in Team Langdon Vs. Team Santos

THE PITT Cast Reveals Their Secret Audition Stories With Noah Wyle & Co-Stars | Behind The Scenes
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THE PITT Cast Reveals Their Secret Audition Stories With Noah Wyle & Co-Stars | Behind The Scenes

'The Pitt' Star Isa Briones Argues Dr. Trinity Santos Is "Not As Evil As People Make Her Out To Be"
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'The Pitt' Star Isa Briones Argues Dr. Trinity Santos Is "Not As Evil As People Make Her Out To Be"

Here in Hollywood: The story behind the Filipino lullaby that made it to 'The Pitt' | ABS-CBN News
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Here in Hollywood: The story behind the Filipino lullaby that made it to 'The Pitt' | ABS-CBN News

‘The Pitt’ Cast Reflect Back on Season 1 and Tease What's to Come in Season 2
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‘The Pitt’ Cast Reflect Back on Season 1 and Tease What's to Come in Season 2