Journal Club Global: Infertility and Subclinical Hypothyroidism

Fertility and Sterility is proud to partner with the University of Pennsylvania Fellows to present this Journal Club Global Live! Practice Committee opinions and guidelines in medicine serve different roles, with the former offering expert insights and the latter providing structured evidence-based recommendations. Subclinical hypothyroidism (SCH) is diagnosed by elevated TSH levels despite normal T4 and T3 levels. The impact of treating SCH on fertility, obstetric outcomes, and offspring neurocognitive development is debated in the literature. The new guideline suggests evidence-based changes in SCH management, focusing on updated diagnostic and treatment criteria to guide practitioners in optimizing patient outcomes. View the Article being discussed: Subclinical hypothyroidism in the infertile female population: a guideline Questions to be addressed: What is the difference between a Practice Committee opinion versus guideline? What defines subclinical hypothyroidism? Does treatment of SCH improve fertility and obstetric outcomes? Does treatment of SCH improve offspring neurocognitive development? · What changes in practice did the new guideline recommend? Panelists:  Jennifer Eaton, MD Clarissa Gracia, MD Micah Hill, DO Suleena Kalra, MD Leigh Humphries, MD Moderator: Kurt Barnhart, MD