Can Camizestrant Change HR+ Breast Cancer Care?— with Drs. Caitlin Taylor & Andrew Davis

A new approach to treating endocrine resistance may be emerging in metastatic HR-positive breast cancer with the SERENA-6 trial. Dr. Caitlin Taylor and Dr. Andrew Davis discuss the SERENA-6 trial and the potential role of camizestrant in patients with ESR1-mutated metastatic breast cancer. The conversation explores how ctDNA monitoring may allow clinicians to detect resistance earlier, intervene before radiographic progression, and potentially keep patients on first-line therapy longer. The discussion covers: • The design and significance of SERENA-6 • ESR1 mutations and endocrine resistance • ctDNA monitoring and molecular progression • Why early intervention may matter • Camizestrant efficacy and ctDNA clearance • Quality of life implications • Oral SERDs versus later-line therapies • Clinical implementation challenges • Monitoring frequency and patient communication • Future applications of ctDNA-guided treatment As molecular monitoring becomes increasingly integrated into oncology practice, understanding how trials like SERENA-6 may reshape treatment decisions is essential. Watch the full discussion and subscribe for more expert oncology conversations from Community Health Media. #CommunityHealthMedia #CHM #BreastCancer #MetastaticBreastCancer #HRPositiveBreastCancer #ERPositiveBreastCancer #Camizestrant #SERENA6 #ESR1 #ctDNA #LiquidBiopsy #OralSERD #EndocrineResistance #CDK46 #PrecisionOncology #BreastOncology #MedicalOncology #CaitlinTaylor #AndrewDavis – Thanks for watching! Our podcasts are also available on: • Spotify - https://spotf.fi/chm-podcast • Amazon Music - https://amazn.so/chm-podcast • Apple Podcast - https://podcasts.apple.com/us/podcast... • Castbox - https://castbox.fm/vh/6735434 • Goodpods - https://goodpods.com/profile/chm-111066 • iHeartRadio - https://iheart.com/podcast/291542082 • Pocket Casts - https://pca.st/3ncdh11o – Community Health Media (CHM) is your full service healthcare communications partner, combining our production expertise with targeted multi-channel campaigns. We connect companies and healthcare brands with key opinion leaders, patients, and consumers through compelling content and live experiences. We’re an integrated marketing company that produces world-class content and curated peer to peer live experiences. We specialize in: • Peer to peer interviews, panels & round-tables • Curated live events & conferences • Professional in-depth content & research updates • Interactive learning modules & webinars • Live & on-demand webcasts & podcasts Learn more about us here - https://communityhealth.media