Dr. Richard Frye, MD, PhD: All about Leucovorin & Benefits for the Autistic Phenotype

For this episode, we discuss the roles and sensitivity of mitochondria with Dr. Richard Frye, MD, PhD. Dr. Frye received an MD and a PhD in Physiology and Biophysics from Georgetown University. He is board certified in Pediatrics, Neurology with special competence in Child Neurology, and as a Certified Principal Investigator. In addition, he has a Masters in Biomedical Sciences and Biostatistics from Drexel University. Dr. Frye has over 300 publications in leading journals and book chapters. Dr. Frye shares many figures during the conversation so the listener can follow along. Dr. Richard Frye https://drfryemdphd.com Rossingnol Medical Center Facebook   / rossignolmedicalcenter   Neurological Health Foundation https://neurologicalhealth.org Healthy Child Guide https://neurologicalhealth.org/the-gu... @daylightco Daylight Computer Company https://daylightcomputer.com?sca_ref=... use "autism" in the discount code for $25 coupon. @getchroma Chroma Light Therapy https://getchroma.co/?ref=autism use "autism" for a 10% discount 0:00 Dr. Richard Frye 0:58 Daylight Computer Company 5:17 Chroma Light Devices 8:27 History of Leucovorin; low risk, high reward; Folate Receptor Alpha (FRa) 10:25 Blood Brain Barrier; Folate; CSF (cerebral spinal fluid) 14:04 DNA, RNA; MTHFR (Methylenetetrahydrofolate reductase) 17:34 Cerebral Folate deficiency; BH4, Placenta & Womb 23:35 Folate deficiency & Autism 26:21 Clinical Studies & Data 29:28 Folate & Mitochondria; Cerebral Folate Antibodies; White Matter Findings (!) 34:45 Cerebral Folate deficiency & Ranges; Autistic Phenotypes: Language, Communication, & Behaviors 40:45 Language & Communication; Self-Injurious Behaviors; Hyperactivity, Agitation; Treatment duration 42:53 Folate Autoantibodies & Maternal Health & Markers 45:30 Studies & Behavioral outcomes; inflammation & thyroid findings 46:58 Neural development; Language connections, white matter tracts & distal connections 48:53 Leucovorin for different severity/levels of Autism; Spinal Bifida 51:08 Preparing for pregnancy 53:50 Transgenerational aspects of Folate Autoantibodies Research; Prenatal Care & Awareness 59:32 Guidance & Support X: https://x.com/rps47586 Hopp: https://www.hopp.bio/fromthespectrum YT:    / @fromthespectrum   email: [email protected] ‪@FromTheSpectrum‬