HIV-Associated Neurocognitive Disorders (HAND) | A Clinical Medicine Brief

🧠 NEURO101: HIV-Associated Neurocognitive Disorders (HAND) | Clinical Medicine Brief | Pro-PA Podcast In this NEURO101 Clinical Medicine Brief, we’re diving into HIV-Associated Neurocognitive Disorders (HAND)—a spectrum of cognitive, motor, and behavioral changes seen in people living with HIV. Though often underdiagnosed, HAND is a critical neurologic consideration for both PANCE prep and clinical practice. 🎯 In this episode, we’ll cover: What is HAND? From Asymptomatic Neurocognitive Impairment (ANI) to HIV-Associated Dementia (HAD) Pathophysiology: Chronic immune activation, viral reservoirs in the CNS Common symptoms: Memory loss, attention deficits, slowed processing, gait disturbance Diagnosis: Clinical evaluation, exclusion of other causes, neuropsych testing Importance of ruling out opportunistic infections (e.g., PML, toxoplasmosis, CMV) MRI findings: Often nonspecific but may show white matter changes Treatment: ART optimization, CNS-penetrating regimens, cognitive support strategies Clinical pearls: Recognizing HAND in long-term survivors, older adults, and low CD4 counts This episode equips you to recognize and manage one of HIV’s most underappreciated complications—before it gets missed. 🎧 Listen on Spotify: https://open.spotify.com/show/2gn5uJP... 🔔 Subscribe on YouTube:    / @profgpac   #ProPAPodcast #NEURO101 #HIVNeurocognitiveDisorders #HAND #HIVDementia #ClinicalMedicineBrief #PANCEPrep #PAStudent #HIVNeurology #PAEducation HIV neurocognitive disorder podcast, HAND diagnosis, HIV dementia symptoms, cognitive decline HIV, HIV encephalopathy, HIV brain fog, PANCE HIV review, white matter changes MRI HIV, CNS-penetrating ART