Muscular Dystrophy | Types and Mutations

Muscular dystrophies (MD) are a genetically and clinically heterogeneous group of rare neuromuscular diseases that cause progressive weakness and breakdown of skeletal muscles over time.The disorders differ as to which muscles are primarily affected, the degree of weakness, how fast they worsen, and when symptoms begin.[1] Some types are also associated with problems in other organs. Muscular dystrophies are caused by mutations in genes, usually those involved in making muscle proteins.These mutations are either inherited from parents or may occur spontaneously during early development.Muscular dystrophies may be X-linked recessive, autosomal recessive, or autosomal dominant. Types : Becker muscular dystrophy Congenital muscular dystrophy Duchenne muscular dystrophy Emery–Dreifuss muscular dystrophy Facioscapulohumeral muscular dystrophy Limb–girdle muscular dystrophy Oculopharyngeal muscular dystrophy