Triple-negative breast cancer: Signs, symptoms and treatment options

Dr. Foluso Ademuyiwa shares recent advancements in the treatment of triple-negative breast cancer (TNBC) and her research on its overlap with health disparities. Moderated by Janine Guglielmino, LBBC's Vice President of Mission Delivery, Dr. Ademuyiwa answers audience questions about symptoms, side-effects, and treatment options for early-stage and metastatic TNBC. This session also addresses concerns about diagnosis, recurrence, BRCA mutations, and care to help you feel confident to make the best decisions for you. About our expert: Dr. Ademuyiwa, is a breast medical oncologist, associate professor at Washington University in St. Louis, and a published researcher. She is an expert in the management of all types of breast cancer and is actively involved in research on triple-negative breast cancer. Read more about Dr. Ademuyiwa: https://www.lbbc.org/about-us/speaker... For more information on TNBC, visit: https://www.lbbc.org/about-breast-can... Chapters: 00:00-02:20 Defining TNBC 02:21-5:49 Recent advancements in TNBC treatment 05:50-07:37 TBNC & health disparities 07:38 – 08:59 Targeted therapies for TNBC that is not BRCA+ 09:00 – 11:23 Is TNBC heterogeneous? 11:24 – 13:13 Key factors in prognosis 13:14 – 15:23 Long-term outcomes without chemo 15:24 – 16:41 Changing treatment schedules 16:42 – 19:19 Estrogen percentages 19:20 – 21:10 Recurrence 21:11 – 24:24 Future prevention with BRCA mutation 24:25 – 26:18 Immunotherapy 26:19 – 28:07 Trodelvy schedule 28:08 – 29:20 Improvements for Black women 29:21 – 29:57 Are there other immunotherapies? 29:58 – 31:16 Cooccurring illnesses with metastatic TNBC 31:17 – 33:11 Outcomes & BRCA mutations 33:12 – 35:05 Outcomes with TNBC and metastatic TNBC 35:06 – 37:00 Capecitabine effectiveness 37:01 – 38:36 Where can TNBC metastasize? 38:37 – 40:06 Preventing recurrence 40:07 – 41:52 Defining early-stage vs late-stage 41:53 – 43:00 DCIS & TNBC 43:01 – 44:09 TNBC & pregnancy 44:10 – 45:06 KEYNOTE clinical trial 45:07 – 46:21 Promising treatments for metastatic TNBC 46:22 – 48:00 Getting immunotherapy after-the-fact 48:01 – 50:24 Chemo & radiation after mastectomy 50:25 – 52:32 Chemo before surgery 52:32 – 54:11 treatments & outcomes for older people 54:12: - 55:41 Going back to chemo after an ADC 55:42 – 56:56 Treatment & outcomes for two different diagnoses 56:57 – 58:21 How a chemo regimen is chosen 58:22 – 58:46 Clinical trials available with vaccines 58:46 – 1:01:38 CtDNA tests 1:01:38 – 1:02:52 Covid-19 vaccine & TNBC 1:01:52 – 1:03:49 How long to take immunotherapy 1:03:50 – 1:05:35 How to get the best outcomes At Living Beyond Breast Cancer, we make sure people facing breast cancer have the support they need. We’re here with real answers, real stories, and real help—every step of the way. Follow us: Facebook:   / livingbeyondbreastcancer   LinkedIn:   / living-beyond-breast-cancer   Instagram:   / livingbeyondbc   YouTube:    / lbbc1991   #TNBC #TripleNegativeBreastCancer