ОЛАНЗАПИН: Почему на нём люди набирают по 30 кг и не могут перестать есть? | История для сна

This "Sleep Story" is the story of olanzapine, one of the most well-known antipsychotic drugs in modern psychiatry. It's a medication that has helped millions of patients worldwide cope with severe mental disorders, but also gained a reputation for dramatically altering appetite, metabolism, and body weight. Why do many olanzapine patients experience near-constant hunger? How did a drug designed to treat serious mental illnesses become linked to one of the most debated issues in modern psychopharmacology? And why do doctors continue to prescribe it despite its known side effects? In this issue: ▪️ The Birth of a Drug: How Scientists Searched for a More Effective and Safe Generation of Antipsychotics ▪️ How Olanzapine Works: Its Effect on Dopamine, Serotonin, and Other Brain Receptors ▪️ A Revolution in Psychiatry: Why the Drug Quickly Became One of the Most Popular in the World ▪️ The Phenomenon of Increased Appetite: Why Many Patients Start Eating Significantly More Than Usual ▪️ Weight Gain and Metabolism: What Happens to the Body During Long-Term Therapy ▪️ Benefits and Risks: Why the Drug's Effectiveness Forces Doctors to Find a Balance Between Results and Side Effects ▪️ Myths and Reality: Does Olanzapine Inevitably Lead to Significant Weight Gain? ▪️ A History Lesson: How Modern Psychiatry Addresses the Issue of Effectiveness and Quality of Life for Patients Simultaneously !!! IMPORTANT WARNING!!! This audio lecture is not medical advice or a guide to action, but purely a historical and popular science study. The video covers the history of psychiatry, the development of antipsychotic medications, and the safety of medication treatment. Any medication should be used only as prescribed by a physician. 00:00:00 Introduction 00:00:54 Alanzapine and its effects 00:01:51 Disruption of harmony in the brain 00:02:49 Search for new drugs 00:04:38 Creation of Alanzapine 00:05:27 Effectiveness of Alanzapine 00:07:21 The downside of Alanzapine 00:09:38 Mechanism of action of Alanzapine on the hypothalamus 00:12:29 Consequences of receptor blockade 00:14:43 Effect of Alanzapine on metabolism 00:15:39 Risks of metabolic syndrome 00:16:38 Choosing between mental and physical health 00:17:33 Return to the doctor 00:18:22 Conclusion of the first part 00:19:12 Depth experiences 00:19:31 The effect of alanzopine on weight 00:20:30 The reaction of others and guilt 00:22:27 The role of the microbiome 00:25:15 Impact on the reward system 00:27:09 Medical consequences and the search for solutions 00:28:05 Use of medformin and topiramate 00:30:10 Symbyax and problems with alanzopine 00:31:06 Searching for a solution 00:32:04 The idea of ​​blocking opioid receptors 00:33:05 Clinical trials and results 00:34:03 Approval and prospects 00:38:06 Emotional consequences of taking alanzopine 00:42:28 Acceptance and self-compassion 00:44:44 A new system of self-care 00:45:36 Change Diet 00:46:36 Brain Adaptation 00:47:31 The Role of Movement 00:49:27 Healing the Body 00:51:26 Modern Psychiatry 00:53:06 The Future of Medicine 00:55:01 Conclusion 00:57:26 Nighttime Meditation 00:58:20 Research Summary 00:59:18 Relaxation and Peace 00:59:36 Overcoming Problems 01:00:29 Rest and Silence 01:01:24 Conclusion