Прогестерон при беременности. Влияние прогестерона на иммунную систему и риск гипофибринолиза.

Progesterone during pregnancy. The effect of progesterone on the immune system and the risk of hypofibrinolysis. Sign up for an online consultation at the CIR by following the link https://vk.cc/9LJxc9 ​ In this video, Dr. Guzov, the creator of the CIR https://vk.cc/9z2aLK, answers the question: "I read an article that progesterone signals the immune system that pregnancy has occurred and suppresses aggressive immunity. Can I have your opinion on this?" That's true, progesterone does block a little, but there is one problem here. That's true, progesterone does give a slight shift in the immune system to some extent. But here we very often encounter the problem of hemostasis. Because very often patients with problems related to reproductive health have not only immune factors, but also factors related to the so-called hypofibrinolysis, that is, hypofibrinolysis is a condition when there may be no problems with the rate of thrombus formation, but there are problems with the dissolution of thrombi. If this dissolution of thrombi occurs somewhat slowly, then here we have a problem during pregnancy. This is revealed by the detection of polymorphisms of the gene serpin one, PLAT, factor 12 and factor 13A1. That is, there are several genes that are responsible for hypofibrinolysis. Plus there is a constitutional factor of hypofibrinolysis - excess weight and plus there is a factor when there are polymorphisms of the gene of vascular tone AC - angiotensin-converting enzyme, AGT angiotensinogen and cip11b2 - aldosterone synthetase. If there is a set of indicators that characterize hypofibrinolysis, the risks of venous thrombosis, thromboembolism and impaired placental function at later stages, then progesterone preparations can sharply increase the risk of venous thrombosis. Without large doses of progesterone, everything would be fine, but against the background of the appointment of large doses of progesterone, we will receive the risk of thrombosis. Therefore, we cannot use progesterone as some kind of immunosuppressive factor. That is, we sometimes prescribe very soft support aimed at supporting early pregnancy. As a rule, this is a small amount, a very verified amount of Utrozhestan. You can sign up for an online consultation by following the link https://vk.cc/9LJxc9​. Find out how to get tested at the CIR if you don’t live in Moscow https://vk.cc/ak3guR ​ You can make an appointment for an in-person consultation by calling the multi-channel number +7 (495) 514-00-11 or on our website at https://vk.cc/9z2cyu ​ Our doctors ​Our website https://vk.cc/9z2aLK ​Laboratory https://vk.cc/9z2b91 ​We are on Facebook   / cironline   ​Our Instagram   / cironline_l.  . ​We are on Vkontakte https://vk.com/socialnetcir ​ Center for Immunology and Reproduction (CIR) https://vk.cc/9z2aLK- ​a network of fertility, obstetrics and prenatal diagnostics clinics with its own medical analysis laboratory "CIR Laboratories" https://vk.cc/9z2b91 ​. We have been working since 1996. Main areas of activity: diagnostics and treatment of infertility and miscarriage preparation for IVF pregnancy planning and pregnancy management urology and andrology assistance and prevention of severe pregnancy complications, preeclampsia, APS, thrombophilia all types of tests. We help people become parents even in the most difficult cases! Our channel is dedicated to obstetrics, gynecology and reproductive medicine. We publish videos about medical news, reviews of articles from foreign scientific journals, analysis of complex clinical cases, and also answer subscribers' questions in our videos. Our videos will be useful for doctors of various specialties whose work is related to reproductive medicine, as well as for patients and a wide range of people interested in obstetrics and gynecology and looking for answers to their questions. On Mondays, at 14.30 Moscow time, our channel hosts live broadcasts with a candidate of medical sciences, obstetrician-gynecologist, Igor Ivanovich Guzov, in which he talks about medical news and answers your questions. Subscribe to our channel so as not to miss broadcasts and the release of new videos! This video    • Прогестерон при беременности. Влияние прог...   Other videos about ​Many interesting videos https://goo.gl/64X3c1 ​ #CIR #Guzov #progesterone #pregnancy #obstetrics #hemostasis #hypofibrinolysis