Conférence - AL BENABID - La Stimulation Cérébrale Profonde - Académie des sciences

Lecture by Alim-Louis BENABID entitled Deep Brain Stimulation 00:00:00 Deep Brain Stimulation 00:02:33 Parkinson's Disease: What is it? 00:04:22 What can be done? 00:08:28 Other Solutions? Experimental Research 00:09:29 Other Solutions? Serendipity 00:12:40 High-Frequency SCP 00:14:29 SCP: A Robust and Effective Surgical Therapy 00:16:04 Current Indications: HF vs. BF 00:20:42 Current Indications: Dystonias 00:22:28 SHF Suggests New Concepts 00:24:47 Pharmaco-Electrical Similarities 00:26:48 SHF Restores, Does Not Recreate 00:29:37 New Indications: Vascular Pain 00:30:32 New Indications: Psychosurgery 00:31:26 New Indications: Mental Disorders, Obsessive-Compulsive Disorder, Depression 00:34:01 New Indications: Eating Disorders 00:35:24 The Mechanism Is Not Unique 00:36:44 Axon-Cell Uncoupling, Synaptic Decay 00:37:28 Neuroprotection is the Holy Grail 00:39:27 1: 60HDA Rat Program, STN KA Lesion 00:40:10 2: MPTP Primates, STN SHF vs Lesion 00:41:12 3: Parkinsonian Patients, SHF of STN 00:42:25 4: Near-Infrared Photomodulation 00:43:56 I. External Illumination NIR 670nm 00:44:43 RESULTS: behavior 00:45:18 II. NIR Endoventricular Preclinical Programs 00:47:19 Preclinical Program: Neuroprotection 00:49:41 Clinical Trial: Neuroprotection 00:51:05 Comments and Conclusion 00:51:28 Supporters 00:51:30 Team 00:51:42 Clinatec 00:52:06 Questions © French Academy of Sciences - All rights reserved