2nd Long COVID Symposium of the German Centers for Health Research (DZG)

The event brings together leading experts to discuss the latest findings on Long COVID. This interdisciplinary symposium will focus on advancing research and improving care for those affected by the condition while fostering collaboration across scientific disciplines. 00:00:00 Opening Stefanie Dimmeler (Frankfurt am Main), Werner Seeger (Gießen) 00:02:05 Welcoming address Veronika von Messling (Berlin, BMFTR - formerly BMBF) 00:18:24 Session 1: Cardiovascular Disease / DZHK Chair: Philipp Wild (Mainz), Stefanie Dimmeler (Frankfurt am Main) 00:18:24 Myoflame-19 – RCT to improve cardiac symptoms and exercise tolerance by targeting endothelial dysfunction – Valentina Puntmann (Frankfurt am Main) 00:33:20 Thrombo-inflammation in COVID-19 – Konstantin Stark (München) 00:52:22 Session 2: Metabolic Disease / DZD, DKTK Chair: Silke Andrich (Düsseldorf), Alexandra Nieters (Freiburg) 00:52:22 Persistent symptoms in post-COVID-19 two years after infection: EPILOC study results – Alexandra Nieters (Freiburg) 01:12:50 Diabetes and postinfectious syndromes – Stefan Bornstein (Dresden) 01:32:40 SARS-CoV-2 NSP1 inhibits insulin granule biogenesis and secretion granules but not MHC-class I expression and traffic in beta-cells – Klaus Knoch (Dresden) 01:46:25 Session 3: Neurological and Immunological Aspects of Long COVID / DZNE Chair: Anna Aschenbrenner, Marc Beyer (both Bonn) 01:46:25 Clinical insights into neurological post-COVID syndrome: Findings from the NEUROCOV project – Omid Shirvani (Bonn) 02:05:40 Towards precision medicine: Single-cell omics and biomarker development in NEUROCOV – Marc Beyer (Bonn) 02:24:05 Immune dysregulation in long COVID and ME/CFS: Insights from single-cell RNA-sequencing studies – Anna Aschenbrenner (Bonn) 02:36:31 Session 4: Mental Health and Sleep Disorders / DZPG Chair: Martin Walter (Jena) 02:38:31 Ability to work after COVID-19: A machine learning model based on clinical parameters Tarek Jebrini (München) 02:49:20 SLEEP-NEURO-PATH: Contribution of sleep-related biomarkers to the pathophysiology of ME/CFS Claudia Schilling (Mannheim) 03:06:10 FEDORA: Post-COVID soon no longer a blind spot? Martin Walter (Jena) 03:25:21 Young Investigator Session Rapid fire talks 03:25:31 Julian Wagner (Frankfurt) — Cardiac Fibrosis and Denervation in Long COVID: The Role of Pre-Existing Cardiovascular Disease 03:29:27 Gani Oruqaj (Gießen) — Ventilatory inefficency and low cardiac preload in Post-Covid-19 associated dyspnea 03:33:15 Georg Fritz Kurze (Dresden) — Parasympathetic inflexibility as a potential central factor precipitating and perpetuating post-COVID-19 exhaustion symptoms: a one-year longitudinal study 03:36:00 Giovanni Vardiero (Tübingen) — Evaluating tVNS for enhancing motivation and recovery in Long COVID: a randomized cross-over study 03:40:32 Rieke Baumkötter (Mainz) — Risk tools for predicting long-term sequelae based on symptom profiles after known and undetected SARS-CoV-2 infections in the population 03:43:22 Sepehr Golriz Khatami (Mainz) — Proteomic atlas of post-COVID sequelae 03:46:47 Session 5: Pulmonary Complications of Long COVID / DZL Chairs: Susanne Herold (Gießen), Rembert Koczulla 03:46:55 Deep clinical phenotyping – Natascha Sommer (Gießen) 04:02:02 Mass spectrometry-based profiling of autoantibodies post-viral infections – Herbert Schiller (München) 04:16:25 Long COVID 19: new insights using functional lung MRI –Jens Vogel-Claussen (Hannover) 04:27:50 COVIDOM+: A population-based study on long-term consequences of COVID-19 –Jan Heyckendorf (Kiel) 04:41:00 Session 6: Immunology and Infection Research in Long COVID / DZIF Chair: Hans-Georg Kräusslich (Heidelberg) 04:41:15 Challenges in the conduct of clinical trials on post COVID syndrome – Maria Vehreschild (Frankfurt am Main) 04:57:44 Immunological aspects of long COVID depending on initial infection severity before vaccination – Christine Falk (Hannover) 05:14:36 Long-term innate and adaptive immune alterations in systemic and tissue-resident compartments following COVID-19 – Clara Lehmann (Köln) 05:29:00 Session 7: Pediatric and Adolescent Health in Long COVID / DZKJ Chair: Klaus-Michael Debatin (Ulm) 05:31:55 Multisystem inflammatory syndrome is linked to viral reactivation – Tilmann Kallinich (Berlin) 05:46:53 Health and well-being of children and adolescents during and after the COVID-19 pandemic – Ulrike Ravens-Sieberer (Hamburg) 06:04:43 Long COVID in pediatrics: What's new? – Nicole Töpfner (Dresden) 06:17:00 Panel Discussion Die Zukunft der Long-COVID-Forschung – Was brauchen Patientinnen und Patienten? Panelists: • Johanna Theobald (Long COVID Deutschland) • Martin Walter (Ärzte- und Ärztinnenverband Long COVID) Moderation: Stefanie Dimmeler, Werner Seeger