Autoimmune Thyroiditis: Hashimoto’s Thyroiditis & Graves’ Disease Explained | Dr. Priyanka Sachdev

Master the essentials of Autoimmune Thyroid Disorders in this high-yield "Prof Buster" session. We break down the anatomical and physiological basics of the thyroid gland before diving deep into the pathophysiology of Graves' Disease and Hashimoto’s Thyroiditis. This video is essential for MBBS 2nd-year pathology, covering hallmark features like "Hurthle cells," "TSI antibodies," and the classic "Eye Signs" of hyperthyroidism. Key Topics Covered: Thyroid Basics: Follicular cells, parafollicular (C) cells, and the 5-step T3/T4 synthesis [02:16]. Regulation: The Hypothalamus-Pituitary-Thyroid (HPT) axis and negative feedback [12:08]. Graves’ Disease: Stimulatory antibodies (TSI/LATS) against TSH receptors [23:54]. Clinical Eye Signs: Kocher, Dalrymple, Von Graefe, and Stellwag signs [32:59]. Hashimoto’s Thyroiditis: Breakdown of self-tolerance and destruction by T-cells & B-cells [43:52]. Histology: Papillary in-foldings (Graves) vs. Germinal centers and Hurthle cells (Hashimoto's) [54:35]. Download the high-yield Thyroid Pathology comparison table and PDF notes on the MedLive App! #Pathology #Thyroiditis #GravesDisease #Hashimoto #MedLive #DrPriyankaSachdev #MBBS #NEETPG #FMGE #MedicalEducation #Endocrinology